Studies on Chemical Constituents of Antitumor Fraction from Periploca sepium. IV. Structures of New Pregnane Glycosides, Periplocosides D, E, L, and M

Hideji Itokawa, Junping Xu, Koichi Takeya

Research output: Contribution to journalArticle

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Four new pregnane glycosides and a known pregnane glycoside (named periplocoside D, E, L, M, and N, respectively), as well as a steroidal compound S-20, have been isolated from the antitumor fraction of Periploca sepium (Asclepiadaceae). Their structures were established by chemical and spectroscopic methods. S-20 was obtained from this plant for the first time.

Original languageEnglish (US)
Pages (from-to)2084-2089
Number of pages6
JournalChemical and Pharmaceutical Bulletin
Issue number6
StatePublished - Jan 1 1988



  • 13C-NMR
  • Asclepiadaceae
  • Periploco sepium
  • periplocoside
  • pregnane glycoside

ASJC Scopus subject areas

  • Chemistry(all)
  • Drug Discovery

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