Studies on Chemical Constituents of Antitumor Fraction from Periploca sepium. IV. Structures of New Pregnane Glycosides, Periplocosides D, E, L, and M

Hideji Itokawa; Junping Xu; Koichi Takeya

doi:10.1248/cpb.36.2084

Studies on Chemical Constituents of Antitumor Fraction from Periploca sepium. IV. Structures of New Pregnane Glycosides, Periplocosides D, E, L, and M

Hideji Itokawa, Junping Xu, Koichi Takeya

Arizona State University

Research output: Contribution to journal › Article › peer-review

57 Scopus citations

Abstract

Four new pregnane glycosides and a known pregnane glycoside (named periplocoside D, E, L, M, and N, respectively), as well as a steroidal compound S-20, have been isolated from the antitumor fraction of Periploca sepium (Asclepiadaceae). Their structures were established by chemical and spectroscopic methods. S-20 was obtained from this plant for the first time.

Original language	English (US)
Pages (from-to)	2084-2089
Number of pages	6
Journal	Chemical and Pharmaceutical Bulletin
Volume	36
Issue number	6
DOIs	https://doi.org/10.1248/cpb.36.2084
State	Published - 1988

Keywords

13C-NMR
Asclepiadaceae
Periploco sepium
periplocoside
pregnane glycoside

ASJC Scopus subject areas

General Chemistry
Drug Discovery

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10.1248/cpb.36.2084

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AU - Xu, Junping

AU - Takeya, Koichi

PY - 1988

Y1 - 1988

N2 - Four new pregnane glycosides and a known pregnane glycoside (named periplocoside D, E, L, M, and N, respectively), as well as a steroidal compound S-20, have been isolated from the antitumor fraction of Periploca sepium (Asclepiadaceae). Their structures were established by chemical and spectroscopic methods. S-20 was obtained from this plant for the first time.

AB - Four new pregnane glycosides and a known pregnane glycoside (named periplocoside D, E, L, M, and N, respectively), as well as a steroidal compound S-20, have been isolated from the antitumor fraction of Periploca sepium (Asclepiadaceae). Their structures were established by chemical and spectroscopic methods. S-20 was obtained from this plant for the first time.

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KW - Asclepiadaceae

KW - Periploco sepium

KW - periplocoside

KW - pregnane glycoside

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Studies on Chemical Constituents of Antitumor Fraction from Periploca sepium. IV. Structures of New Pregnane Glycosides, Periplocosides D, E, L, and M

Abstract

Keywords

ASJC Scopus subject areas

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