Structure of photosystem I

Petra Fromme, Patrick Jordan, Norbert Krauß

Research output: Contribution to journalArticle

310 Citations (Scopus)

Abstract

In plants and cyanobacteria, the primary step in oxygenic photosynthesis, the light induced charge separation, is driven by two large membrane intrinsic protein complexes, the photosystems I and II. Photosystem I catalyses the light driven electron transfer from plastocyanin/cytochrome c6 on the lumenal side of the membrane to ferredoxin/flavodoxin at the stromal side by a chain of electron carriers. Photosystem I of Synechococcus elongatus consists of 12 protein subunits, 96 chlorophyll a molecules, 22 carotenoids, three [4Fe4S] clusters and two phylloquinones. Furthermore, it has been discovered that four lipids are intrinsic components of photosystem I. Photosystem I exists as a trimer in the native membrane with a molecular mass of 1068 kDa for the whole complex. The X-ray structure of photosystem I at a resolution of 2.5 Å shows the location of the individual subunits and cofactors and provides new information on the protein-cofactor interactions. [P. Jordan, P. Fromme, H.T. Witt, O. Klukas, W. Saenger, N. Krauß, Nature 411 (2001) 909-917]. In this review, biochemical data and results of biophysical investigations are discussed with respect to the X-ray crystallographic structure in order to give an overview of the structure and function of this large membrane protein.

Original languageEnglish (US)
Pages (from-to)5-31
Number of pages27
JournalBiochimica et Biophysica Acta - Bioenergetics
Volume1507
Issue number1-3
DOIs
StatePublished - Oct 30 2001
Externally publishedYes

Fingerprint

Photosystem I Protein Complex
Membranes
Cytochromes c6
Membrane Proteins
Flavodoxin
Plastocyanin
X-Rays
Electrons
Vitamin K 1
Synechococcus
Light
Ferredoxins
X rays
Jordan
Photosystem II Protein Complex
Photosynthesis
Protein Subunits
Cyanobacteria
Molecular mass
Carotenoids

Keywords

  • Core antenna
  • Electron transfer chain
  • Membrane protein
  • Photosystem I
  • Structure
  • X-ray crystallography

ASJC Scopus subject areas

  • Biophysics

Cite this

Structure of photosystem I. / Fromme, Petra; Jordan, Patrick; Krauß, Norbert.

In: Biochimica et Biophysica Acta - Bioenergetics, Vol. 1507, No. 1-3, 30.10.2001, p. 5-31.

Research output: Contribution to journalArticle

Fromme, Petra ; Jordan, Patrick ; Krauß, Norbert. / Structure of photosystem I. In: Biochimica et Biophysica Acta - Bioenergetics. 2001 ; Vol. 1507, No. 1-3. pp. 5-31.
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