Steroids and related natural products-xxvii. Salvia apiana

George Pettit, H. Klinger, Nels Otto N Jorgensen, J. Occolowitz

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

The pentacyclic triterpene composition of a southern California variety of Salvia apiana (fam. Labiatae) has been assessed. The presence of α-amyrin, oleanolic acid and ursolic acid has been established. Separation of α-amyrin from a closely related impurity believed to be β-amyrin was accomplished by subjecting the mixture to selenium dioxide oxidation and isolating α-amyrin by preparative thin-layer chromatography on silver nitrate-silica gel. Evidence for the presence of isomeric mixtures of two dihydroxy triterpenes and two triterpene aldehydes representing intermediate stages of oxidation from α- and β-amyrin to ursolic and oleanolic acids was presented. Isolation of ursolic acid from a Mexican variety of Salvia karwinskii was also reported.

Original languageEnglish (US)
Pages (from-to)301-309
Number of pages9
JournalPhytochemistry
Volume5
Issue number3
StatePublished - May 1966
Externally publishedYes

Fingerprint

Salvia
ursolic acid
Biological Products
triterpenoids
steroids
oleanolic acid
Steroids
Oleanolic Acid
Triterpenes
oxidation
silver nitrate
silica gel
Lamiaceae
Selenium Oxides
thin layer chromatography
Pentacyclic Triterpenes
aldehydes
selenium
Silver Nitrate
Thin layer chromatography

ASJC Scopus subject areas

  • Drug Discovery
  • Organic Chemistry
  • Molecular Biology
  • Biochemistry
  • Plant Science

Cite this

Pettit, G., Klinger, H., Jorgensen, N. O. N., & Occolowitz, J. (1966). Steroids and related natural products-xxvii. Salvia apiana. Phytochemistry, 5(3), 301-309.

Steroids and related natural products-xxvii. Salvia apiana. / Pettit, George; Klinger, H.; Jorgensen, Nels Otto N; Occolowitz, J.

In: Phytochemistry, Vol. 5, No. 3, 05.1966, p. 301-309.

Research output: Contribution to journalArticle

Pettit, G, Klinger, H, Jorgensen, NON & Occolowitz, J 1966, 'Steroids and related natural products-xxvii. Salvia apiana', Phytochemistry, vol. 5, no. 3, pp. 301-309.
Pettit G, Klinger H, Jorgensen NON, Occolowitz J. Steroids and related natural products-xxvii. Salvia apiana. Phytochemistry. 1966 May;5(3):301-309.
Pettit, George ; Klinger, H. ; Jorgensen, Nels Otto N ; Occolowitz, J. / Steroids and related natural products-xxvii. Salvia apiana. In: Phytochemistry. 1966 ; Vol. 5, No. 3. pp. 301-309.
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