Steroids and related natural products. 88. Synthesis of periplogenin

Yoshiaki Kamano, George Pettit, M. Tozawa

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Digitoxigenin (3a) was converted to canarigenin (6), periplogenin (1c), and uzarigenin (3b); the use of tert-butyl hypochlorite for oxidation of digitoxigenin (3a) to chloro ketone 4 and application of chromium(II) acetate for reduction of epoxy ketone 7 to hydroxy ketone 8 represented particularly convenient aspects of these synthetic transformations.

Original languageEnglish (US)
Pages (from-to)2319-2320
Number of pages2
JournalJournal of Organic Chemistry
Volume39
Issue number15
StatePublished - 1974

Fingerprint

Digitoxigenin
Biological Products
Ketones
Steroids
Hypochlorous Acid
Chromium
Acetates
Oxidation
periplogenin

ASJC Scopus subject areas

  • Organic Chemistry

Cite this

Steroids and related natural products. 88. Synthesis of periplogenin. / Kamano, Yoshiaki; Pettit, George; Tozawa, M.

In: Journal of Organic Chemistry, Vol. 39, No. 15, 1974, p. 2319-2320.

Research output: Contribution to journalArticle

Kamano, Yoshiaki ; Pettit, George ; Tozawa, M. / Steroids and related natural products. 88. Synthesis of periplogenin. In: Journal of Organic Chemistry. 1974 ; Vol. 39, No. 15. pp. 2319-2320.
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