Static behavioral effects on gonorrhea transmission dynamics in a MSM population

Benjamin R. Morin; Liana Medina-Rios; Erika Camacho; Carlos Castillo-Chavez

doi:10.1016/j.jtbi.2010.07.027

Static behavioral effects on gonorrhea transmission dynamics in a MSM population

Benjamin R. Morin, Liana Medina-Rios, Erika Camacho, Carlos Castillo-Chavez

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

An SIS/. SAS model of gonorrhea transmission in a population of highly active men-having-sex-with-men (MSM) is presented in this paper to study the impact of safe behavior on the dynamics of gonorrhea prevalence. Safe behaviors may fall into two categories-prevention and self-awareness. Prevention will be modeled via consistent condom use and self-awareness via STD testing frequency. Stability conditions for the disease free equilibrium and endemic equilibrium are determined along with a complete analysis of global dynamics. The control reproductive number is used as a means for measuring the effect of changes to model parameters on the prevalence of the disease. We also find that appropriate intervention would be in the form of a multifaceted approach at overall risk reduction rather than tackling one specific control individually.

Original language	English (US)
Pages (from-to)	35-40
Number of pages	6
Journal	Journal of Theoretical Biology
Volume	267
Issue number	1
DOIs	https://doi.org/10.1016/j.jtbi.2010.07.027
State	Published - Nov 2010

Keywords

Gonorrhea
Mathematical epidemiology

ASJC Scopus subject areas

Statistics and Probability
Modeling and Simulation
General Biochemistry, Genetics and Molecular Biology
General Immunology and Microbiology
General Agricultural and Biological Sciences
Applied Mathematics

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title = "Static behavioral effects on gonorrhea transmission dynamics in a MSM population",

abstract = "An SIS/. SAS model of gonorrhea transmission in a population of highly active men-having-sex-with-men (MSM) is presented in this paper to study the impact of safe behavior on the dynamics of gonorrhea prevalence. Safe behaviors may fall into two categories-prevention and self-awareness. Prevention will be modeled via consistent condom use and self-awareness via STD testing frequency. Stability conditions for the disease free equilibrium and endemic equilibrium are determined along with a complete analysis of global dynamics. The control reproductive number is used as a means for measuring the effect of changes to model parameters on the prevalence of the disease. We also find that appropriate intervention would be in the form of a multifaceted approach at overall risk reduction rather than tackling one specific control individually.",

keywords = "Gonorrhea, Mathematical epidemiology",

author = "Morin, {Benjamin R.} and Liana Medina-Rios and Erika Camacho and Carlos Castillo-Chavez",

note = "Funding Information: This project has been partially supported by grants from the National Science Foundation (NSF - Grant DMPS-0838704), the National Security Agency (NSA - Grant H98230-09-1-0104), the Alfred P. Sloan Foundation and the Office of the Provost of Arizona State University. The authors would like to thank the suggestions and effort put forth by Carlos Castillo-Chavez, Christopher Kribs-Zaleta and Baojun Song in order to accomplish the analysis that has been done to the model. ",

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doi = "10.1016/j.jtbi.2010.07.027",

language = "English (US)",

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AU - Morin, Benjamin R.

AU - Medina-Rios, Liana

AU - Camacho, Erika

AU - Castillo-Chavez, Carlos

N1 - Funding Information: This project has been partially supported by grants from the National Science Foundation (NSF - Grant DMPS-0838704), the National Security Agency (NSA - Grant H98230-09-1-0104), the Alfred P. Sloan Foundation and the Office of the Provost of Arizona State University. The authors would like to thank the suggestions and effort put forth by Carlos Castillo-Chavez, Christopher Kribs-Zaleta and Baojun Song in order to accomplish the analysis that has been done to the model.

PY - 2010/11

Y1 - 2010/11

N2 - An SIS/. SAS model of gonorrhea transmission in a population of highly active men-having-sex-with-men (MSM) is presented in this paper to study the impact of safe behavior on the dynamics of gonorrhea prevalence. Safe behaviors may fall into two categories-prevention and self-awareness. Prevention will be modeled via consistent condom use and self-awareness via STD testing frequency. Stability conditions for the disease free equilibrium and endemic equilibrium are determined along with a complete analysis of global dynamics. The control reproductive number is used as a means for measuring the effect of changes to model parameters on the prevalence of the disease. We also find that appropriate intervention would be in the form of a multifaceted approach at overall risk reduction rather than tackling one specific control individually.

AB - An SIS/. SAS model of gonorrhea transmission in a population of highly active men-having-sex-with-men (MSM) is presented in this paper to study the impact of safe behavior on the dynamics of gonorrhea prevalence. Safe behaviors may fall into two categories-prevention and self-awareness. Prevention will be modeled via consistent condom use and self-awareness via STD testing frequency. Stability conditions for the disease free equilibrium and endemic equilibrium are determined along with a complete analysis of global dynamics. The control reproductive number is used as a means for measuring the effect of changes to model parameters on the prevalence of the disease. We also find that appropriate intervention would be in the form of a multifaceted approach at overall risk reduction rather than tackling one specific control individually.

KW - Gonorrhea

KW - Mathematical epidemiology

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Static behavioral effects on gonorrhea transmission dynamics in a MSM population

Abstract

Keywords

ASJC Scopus subject areas

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