Static behavioral effects on gonorrhea transmission dynamics in a MSM population

Benjamin R. Morin; Liana Medina-Rios; Erika Camacho; Carlos Castillo-Chavez

doi:10.1016/j.jtbi.2010.07.027

Static behavioral effects on gonorrhea transmission dynamics in a MSM population

Benjamin R. Morin, Liana Medina-Rios, Erika Camacho, Carlos Castillo-Chavez

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

An SIS/. SAS model of gonorrhea transmission in a population of highly active men-having-sex-with-men (MSM) is presented in this paper to study the impact of safe behavior on the dynamics of gonorrhea prevalence. Safe behaviors may fall into two categories-prevention and self-awareness. Prevention will be modeled via consistent condom use and self-awareness via STD testing frequency. Stability conditions for the disease free equilibrium and endemic equilibrium are determined along with a complete analysis of global dynamics. The control reproductive number is used as a means for measuring the effect of changes to model parameters on the prevalence of the disease. We also find that appropriate intervention would be in the form of a multifaceted approach at overall risk reduction rather than tackling one specific control individually.

Original language	English (US)
Pages (from-to)	35-40
Number of pages	6
Journal	Journal of Theoretical Biology
Volume	267
Issue number	1
DOIs	https://doi.org/10.1016/j.jtbi.2010.07.027
State	Published - Nov 2010

Keywords

Gonorrhea
Mathematical epidemiology

ASJC Scopus subject areas

Statistics and Probability
Modeling and Simulation
Biochemistry, Genetics and Molecular Biology(all)
Immunology and Microbiology(all)
Agricultural and Biological Sciences(all)
Applied Mathematics

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10.1016/j.jtbi.2010.07.027

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title = "Static behavioral effects on gonorrhea transmission dynamics in a MSM population",

abstract = "An SIS/. SAS model of gonorrhea transmission in a population of highly active men-having-sex-with-men (MSM) is presented in this paper to study the impact of safe behavior on the dynamics of gonorrhea prevalence. Safe behaviors may fall into two categories-prevention and self-awareness. Prevention will be modeled via consistent condom use and self-awareness via STD testing frequency. Stability conditions for the disease free equilibrium and endemic equilibrium are determined along with a complete analysis of global dynamics. The control reproductive number is used as a means for measuring the effect of changes to model parameters on the prevalence of the disease. We also find that appropriate intervention would be in the form of a multifaceted approach at overall risk reduction rather than tackling one specific control individually.",

keywords = "Gonorrhea, Mathematical epidemiology",

author = "Morin, {Benjamin R.} and Liana Medina-Rios and Erika Camacho and Carlos Castillo-Chavez",

note = "Funding Information: This project has been partially supported by grants from the National Science Foundation (NSF - Grant DMPS-0838704), the National Security Agency (NSA - Grant H98230-09-1-0104), the Alfred P. Sloan Foundation and the Office of the Provost of Arizona State University. The authors would like to thank the suggestions and effort put forth by Carlos Castillo-Chavez, Christopher Kribs-Zaleta and Baojun Song in order to accomplish the analysis that has been done to the model. ",

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doi = "10.1016/j.jtbi.2010.07.027",

language = "English (US)",

volume = "267",

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AU - Morin, Benjamin R.

AU - Medina-Rios, Liana

AU - Camacho, Erika

AU - Castillo-Chavez, Carlos

N1 - Funding Information: This project has been partially supported by grants from the National Science Foundation (NSF - Grant DMPS-0838704), the National Security Agency (NSA - Grant H98230-09-1-0104), the Alfred P. Sloan Foundation and the Office of the Provost of Arizona State University. The authors would like to thank the suggestions and effort put forth by Carlos Castillo-Chavez, Christopher Kribs-Zaleta and Baojun Song in order to accomplish the analysis that has been done to the model.

PY - 2010/11

Y1 - 2010/11

N2 - An SIS/. SAS model of gonorrhea transmission in a population of highly active men-having-sex-with-men (MSM) is presented in this paper to study the impact of safe behavior on the dynamics of gonorrhea prevalence. Safe behaviors may fall into two categories-prevention and self-awareness. Prevention will be modeled via consistent condom use and self-awareness via STD testing frequency. Stability conditions for the disease free equilibrium and endemic equilibrium are determined along with a complete analysis of global dynamics. The control reproductive number is used as a means for measuring the effect of changes to model parameters on the prevalence of the disease. We also find that appropriate intervention would be in the form of a multifaceted approach at overall risk reduction rather than tackling one specific control individually.

AB - An SIS/. SAS model of gonorrhea transmission in a population of highly active men-having-sex-with-men (MSM) is presented in this paper to study the impact of safe behavior on the dynamics of gonorrhea prevalence. Safe behaviors may fall into two categories-prevention and self-awareness. Prevention will be modeled via consistent condom use and self-awareness via STD testing frequency. Stability conditions for the disease free equilibrium and endemic equilibrium are determined along with a complete analysis of global dynamics. The control reproductive number is used as a means for measuring the effect of changes to model parameters on the prevalence of the disease. We also find that appropriate intervention would be in the form of a multifaceted approach at overall risk reduction rather than tackling one specific control individually.

KW - Gonorrhea

KW - Mathematical epidemiology

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Static behavioral effects on gonorrhea transmission dynamics in a MSM population

Abstract

Keywords

ASJC Scopus subject areas

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