TY - JOUR
T1 - Startling acoustic stimuli elicit rapid hand extension following stroke
AU - Honeycutt, Claire F.
AU - Tresch, Ursina A.
AU - Perreault, Eric J.
N1 - Funding Information:
Acknowledgment. This work was supported by the National Institutes of Health grants R01 NS053813 and K99 HD073240.
Publisher Copyright:
© Springer International Publishing Switzerland 2014.
PY - 2014
Y1 - 2014
N2 - Loud startling acoustic stimuli can involuntarily elicit planned movements faster than is possible voluntarily. This phenomenon, known as startReact, is thought to be mediated through brainstem pathways. The startReact can be elicited in stroke survivors with a cortical lesion. This has been demonstrated for elbow motions, thought to have significant input from brainstem pathways. This study sought to determine if the startReact can also be elicited for hand movements following stroke, even though these are driven predominantly by the motor cortex. Data were collected from 8 stroke survivors performing rapid hand extension movements. StartReact responses could be elicited in 7 of 8 subjects. Across all subjects, the startling acoustic stimuli were able to decrease movement times substantially (Δ 57ms; p ≈ 0) when indicators of startle were detected. However, these responses were elicited less frequently than previous reports for startReact at the elbow. Nevertheless, the intact startReact response suggests that the integrity and actions of the pathways mediating this response should be considered when rehabilitating the hand following stroke.
AB - Loud startling acoustic stimuli can involuntarily elicit planned movements faster than is possible voluntarily. This phenomenon, known as startReact, is thought to be mediated through brainstem pathways. The startReact can be elicited in stroke survivors with a cortical lesion. This has been demonstrated for elbow motions, thought to have significant input from brainstem pathways. This study sought to determine if the startReact can also be elicited for hand movements following stroke, even though these are driven predominantly by the motor cortex. Data were collected from 8 stroke survivors performing rapid hand extension movements. StartReact responses could be elicited in 7 of 8 subjects. Across all subjects, the startling acoustic stimuli were able to decrease movement times substantially (Δ 57ms; p ≈ 0) when indicators of startle were detected. However, these responses were elicited less frequently than previous reports for startReact at the elbow. Nevertheless, the intact startReact response suggests that the integrity and actions of the pathways mediating this response should be considered when rehabilitating the hand following stroke.
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U2 - 10.1007/978-3-319-08072-7_65
DO - 10.1007/978-3-319-08072-7_65
M3 - Article
AN - SCOPUS:85037704355
SN - 2195-3562
VL - 7
SP - 431
EP - 435
JO - Biosystems and Biorobotics
JF - Biosystems and Biorobotics
ER -