Spectroscopic investigation of the metal ligation and reactivity of the ferrous active sites of bleomycin and bleomycin derivatives

Medicine & Life Sciences

• pyrimidine 90%
• Bleomycin 83%
• Catalytic Domain 66%
• Ligation 64%
• Metals 63%
• Circular Dichroism 60%
• Ligands 51%
• Amines 51%
• DNA 41%
• Iron 40%
• Oxygen 34%
• Azides 34%
• imidazole 31%
• Amides 29%
• Mannose 28%
• Spectrum Analysis 24%
• Sugars 23%
• Electrons 19%
• Pharmaceutical Preparations 10%

Engineering & Materials Science

• Ligands 97%
• DNA 75%
• Derivatives 60%
• Amines 58%
• Circular dichroism spectroscopy 50%
• Metals 46%
• Iron 43%
• Circular Dichroism 43%
• Oxygen 39%
• Amides 36%
• Light absorption 36%
• Electronic structure 36%
• Carrier concentration 34%
• Sugars 29%
• Molecules 23%
• Degradation 16%

Chemical Compounds

• Bleomycin 100%
• Pyrimidine 65%
• Coordination Sphere 48%
• Primary Amine 47%
• Magnetic Circular Dichroism Spectroscopy 37%
• Metal 32%
• Ligand 32%
• Carbamoyl 31%
• Mannose 26%
• Secondary Amine 24%
• Dioxygen 23%
• Absorptivity 23%
• Azide 22%
• Electron Density 22%
• Imidazole 21%
• Circular Dichroism 20%
• Kd 18%
• Electronic State 17%
• Amide 17%
• Chemistry 14%
• Environment 13%
• Drug 12%
• Solvent 11%
• Molecule 8%