Somatosensory stimulus entrains spindle oscillations in the thalamic VPL nucleus in barbiturate anesthetized rats

Jitendran Muthuswamy, P. Tran, R. Rangarajan, F. A. Lenz, D. F. Hanley, N. V. Thakor

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

This study reports the effect of external stimuli on spindle oscillations in the somatosensory thalamus of barbiturate anesthetized rats. Multi-unit responses to somatosensory stimuli were measured from the contralateral thalamic ventral posterior lateral (VPL) nucleus at different stimulus strengths and periods. Spindle oscillations could be entrained by the somatosensory stimuli at periods between 2 and 5 s. A resonance phenomenon described as a quiescent pre-stimulus period followed by entrained post-stimulus oscillations, was observed for somatosensory stimuli above the threshold for eliciting cortical evoked potentials and a stimulus period between 2 and 5 s. This study demonstrates an ascending pathway for localized modulation of spindle oscillations.

Original languageEnglish (US)
Pages (from-to)191-194
Number of pages4
JournalNeuroscience Letters
Volume262
Issue number3
DOIs
StatePublished - Mar 12 1999
Externally publishedYes

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Ventral Thalamic Nuclei
Thalamus
Evoked Potentials
barbituric acid

Keywords

  • Spindle oscillations
  • Thalamic ventral posterior lateral (VPL) nucleus

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Somatosensory stimulus entrains spindle oscillations in the thalamic VPL nucleus in barbiturate anesthetized rats. / Muthuswamy, Jitendran; Tran, P.; Rangarajan, R.; Lenz, F. A.; Hanley, D. F.; Thakor, N. V.

In: Neuroscience Letters, Vol. 262, No. 3, 12.03.1999, p. 191-194.

Research output: Contribution to journalArticle

Muthuswamy, Jitendran ; Tran, P. ; Rangarajan, R. ; Lenz, F. A. ; Hanley, D. F. ; Thakor, N. V. / Somatosensory stimulus entrains spindle oscillations in the thalamic VPL nucleus in barbiturate anesthetized rats. In: Neuroscience Letters. 1999 ; Vol. 262, No. 3. pp. 191-194.
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