Somatosensory stimulus entrains spindle oscillations in the thalamic VPL nucleus in barbiturate anesthetized rats

J. Muthuswamy; P. Tran; R. Rangarajan; F. A. Lenz; D. F. Hanley; N. V. Thakor

doi:10.1016/S0304-3940(99)00081-6

Somatosensory stimulus entrains spindle oscillations in the thalamic VPL nucleus in barbiturate anesthetized rats

J. Muthuswamy, P. Tran, R. Rangarajan, F. A. Lenz, D. F. Hanley, N. V. Thakor

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

This study reports the effect of external stimuli on spindle oscillations in the somatosensory thalamus of barbiturate anesthetized rats. Multi-unit responses to somatosensory stimuli were measured from the contralateral thalamic ventral posterior lateral (VPL) nucleus at different stimulus strengths and periods. Spindle oscillations could be entrained by the somatosensory stimuli at periods between 2 and 5 s. A resonance phenomenon described as a quiescent pre-stimulus period followed by entrained post-stimulus oscillations, was observed for somatosensory stimuli above the threshold for eliciting cortical evoked potentials and a stimulus period between 2 and 5 s. This study demonstrates an ascending pathway for localized modulation of spindle oscillations.

Original language	English (US)
Pages (from-to)	191-194
Number of pages	4
Journal	Neuroscience Letters
Volume	262
Issue number	3
DOIs	https://doi.org/10.1016/S0304-3940(99)00081-6
State	Published - Mar 12 1999
Externally published	Yes

Keywords

Spindle oscillations
Thalamic ventral posterior lateral (VPL) nucleus

ASJC Scopus subject areas

General Neuroscience

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10.1016/S0304-3940(99)00081-6

Cite this

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title = "Somatosensory stimulus entrains spindle oscillations in the thalamic VPL nucleus in barbiturate anesthetized rats",

abstract = "This study reports the effect of external stimuli on spindle oscillations in the somatosensory thalamus of barbiturate anesthetized rats. Multi-unit responses to somatosensory stimuli were measured from the contralateral thalamic ventral posterior lateral (VPL) nucleus at different stimulus strengths and periods. Spindle oscillations could be entrained by the somatosensory stimuli at periods between 2 and 5 s. A resonance phenomenon described as a quiescent pre-stimulus period followed by entrained post-stimulus oscillations, was observed for somatosensory stimuli above the threshold for eliciting cortical evoked potentials and a stimulus period between 2 and 5 s. This study demonstrates an ascending pathway for localized modulation of spindle oscillations.",

keywords = "Spindle oscillations, Thalamic ventral posterior lateral (VPL) nucleus",

author = "J. Muthuswamy and P. Tran and R. Rangarajan and Lenz, {F. A.} and Hanley, {D. F.} and Thakor, {N. V.}",

note = "Funding Information: This research was supported by grant NS24282 from the NIH.",

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doi = "10.1016/S0304-3940(99)00081-6",

language = "English (US)",

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T1 - Somatosensory stimulus entrains spindle oscillations in the thalamic VPL nucleus in barbiturate anesthetized rats

AU - Muthuswamy, J.

AU - Tran, P.

AU - Rangarajan, R.

AU - Lenz, F. A.

AU - Hanley, D. F.

AU - Thakor, N. V.

N1 - Funding Information: This research was supported by grant NS24282 from the NIH.

PY - 1999/3/12

Y1 - 1999/3/12

N2 - This study reports the effect of external stimuli on spindle oscillations in the somatosensory thalamus of barbiturate anesthetized rats. Multi-unit responses to somatosensory stimuli were measured from the contralateral thalamic ventral posterior lateral (VPL) nucleus at different stimulus strengths and periods. Spindle oscillations could be entrained by the somatosensory stimuli at periods between 2 and 5 s. A resonance phenomenon described as a quiescent pre-stimulus period followed by entrained post-stimulus oscillations, was observed for somatosensory stimuli above the threshold for eliciting cortical evoked potentials and a stimulus period between 2 and 5 s. This study demonstrates an ascending pathway for localized modulation of spindle oscillations.

AB - This study reports the effect of external stimuli on spindle oscillations in the somatosensory thalamus of barbiturate anesthetized rats. Multi-unit responses to somatosensory stimuli were measured from the contralateral thalamic ventral posterior lateral (VPL) nucleus at different stimulus strengths and periods. Spindle oscillations could be entrained by the somatosensory stimuli at periods between 2 and 5 s. A resonance phenomenon described as a quiescent pre-stimulus period followed by entrained post-stimulus oscillations, was observed for somatosensory stimuli above the threshold for eliciting cortical evoked potentials and a stimulus period between 2 and 5 s. This study demonstrates an ascending pathway for localized modulation of spindle oscillations.

KW - Spindle oscillations

KW - Thalamic ventral posterior lateral (VPL) nucleus

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JO - Neuroscience Letters

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Somatosensory stimulus entrains spindle oscillations in the thalamic VPL nucleus in barbiturate anesthetized rats

Abstract

Keywords

ASJC Scopus subject areas

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