Solitary pulmonary nodule

CT evaluation of enhancement with iodinated contrast material - A preliminary report

Stephen J. Swensen, Richard L. Morin, Beth A. Schueler, Larry R. Brown, Denis Cortese, Peter C. Pairolero, W. Mark Brutinel

Research output: Contribution to journalArticle

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Abstract

The authors hypothesized that the degree of contrast material enhancement of a pulmonary nodule, measured with computed tomography (CT), may indicate the likelihood of malignancy. Fifty-two patients with uncalcified solitary pulmonary nodules (diameter, 6-30 mm) were studied. Five single serial thin-section CT scans were obtained at 1-minute intervals after injection of 100 mL of nonionic contrast material. Twenty-two patients were excluded because the diagnosis was not clearly established: The observation period was less than 2 years, or the examination was technically inadequate. Malignant nodules were identified in 23 of the 30 remaining patients, and benign nodules were identified in seven. Within the first 2 minutes after the injection, all the malignant nodules had enhanced by 20 HU or greater (only one benign nodule had that degree of enhancement). The authors conclude that the degree of contrast material enhancement of pulmonary nodules as measured with CT may indicate the likelihood of malignancy.

Original languageEnglish (US)
Pages (from-to)343-347
Number of pages5
JournalRadiology
Volume182
Issue number2
StatePublished - Feb 1992
Externally publishedYes

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Solitary Pulmonary Nodule
Contrast Media
Tomography
Lung
Injections
Neoplasms
Observation

Keywords

  • Lung neoplasms, CT, 60.1211
  • Lung, CT, 60.1211
  • Lung, neoplasms, diagnosis, 60.31, 60.32
  • Lung, nodule, 60.31, 60.32

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology

Cite this

Swensen, S. J., Morin, R. L., Schueler, B. A., Brown, L. R., Cortese, D., Pairolero, P. C., & Brutinel, W. M. (1992). Solitary pulmonary nodule: CT evaluation of enhancement with iodinated contrast material - A preliminary report. Radiology, 182(2), 343-347.

Solitary pulmonary nodule : CT evaluation of enhancement with iodinated contrast material - A preliminary report. / Swensen, Stephen J.; Morin, Richard L.; Schueler, Beth A.; Brown, Larry R.; Cortese, Denis; Pairolero, Peter C.; Brutinel, W. Mark.

In: Radiology, Vol. 182, No. 2, 02.1992, p. 343-347.

Research output: Contribution to journalArticle

Swensen, SJ, Morin, RL, Schueler, BA, Brown, LR, Cortese, D, Pairolero, PC & Brutinel, WM 1992, 'Solitary pulmonary nodule: CT evaluation of enhancement with iodinated contrast material - A preliminary report', Radiology, vol. 182, no. 2, pp. 343-347.
Swensen SJ, Morin RL, Schueler BA, Brown LR, Cortese D, Pairolero PC et al. Solitary pulmonary nodule: CT evaluation of enhancement with iodinated contrast material - A preliminary report. Radiology. 1992 Feb;182(2):343-347.
Swensen, Stephen J. ; Morin, Richard L. ; Schueler, Beth A. ; Brown, Larry R. ; Cortese, Denis ; Pairolero, Peter C. ; Brutinel, W. Mark. / Solitary pulmonary nodule : CT evaluation of enhancement with iodinated contrast material - A preliminary report. In: Radiology. 1992 ; Vol. 182, No. 2. pp. 343-347.
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