Social exploitation of vitellogenin

Gro Amdam, Kari Norberg, Arne Hagen, Stig W. Omholt

Research output: Contribution to journalArticle

228 Citations (Scopus)

Abstract

Vitellogenin is a female-specific glucolipoprotein yolk precursor produced by all oviparous animals. Vitellogenin expression is under hormonal control, and the protein is generally synthesized directly before yolk deposition. In the honeybee (Apis mellifera), vitellogenin is not only synthesized by the reproductive queen, but also by the functionally sterile workers. In summer, the worker population consists of a hive bee group performing a multitude of tasks including nursing inside the nest, and a forager group specialized in collecting nectar, pollen, water, and propolis. Vitellogenin is synthesized in large quantities by hive bees. When hive bees develop into foragers, their juvenile hormone titers increase, and this causes cessation of their vitellogenin production. This inverse relationship between vitellogenin synthesis and juvenile hormone is opposite to the norm in insects, and the underlying proximate processes and life-history reasons are still not understood. Here we document an alternative use of vitellogenin by showing that it is a source for the proteinaceous royal jelly that is produced by the hive bees. Hive bees use the jelly to feed larvae, queen, workers, and drones. This finding suggests that the evolution of a brood-rearing worker class and a specialized forager class in an advanced eusocial insect society has been directed by an alternative utilization of yolk protein.

Original languageEnglish (US)
Pages (from-to)1799-1802
Number of pages4
JournalProceedings of the National Academy of Sciences of the United States of America
Volume100
Issue number4
DOIs
StatePublished - Feb 18 2003
Externally publishedYes

Fingerprint

Vitellogenins
Bees
Urticaria
Juvenile Hormones
Insects
Oviparity
Plant Nectar
Propolis
Egg Proteins
Pollen
Larva
Nursing
Water

ASJC Scopus subject areas

  • Genetics
  • General

Cite this

Social exploitation of vitellogenin. / Amdam, Gro; Norberg, Kari; Hagen, Arne; Omholt, Stig W.

In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, No. 4, 18.02.2003, p. 1799-1802.

Research output: Contribution to journalArticle

Amdam, Gro ; Norberg, Kari ; Hagen, Arne ; Omholt, Stig W. / Social exploitation of vitellogenin. In: Proceedings of the National Academy of Sciences of the United States of America. 2003 ; Vol. 100, No. 4. pp. 1799-1802.
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