Size-dependent anodic dissolution of water-soluble palladium nanoparticles

2,2′-Bicinchoninic acid-capped palladium nanoparticles (Pd-BCA NPs) were synthesized using a one-pot chemical reduction route. Monodisperse Pd-BCA NPs of different size ranges were obtained using a purification technique employing low molecular weight cutoff centrifuge filters. Size-dependent anodic dissolution of Pd-BCA NPs was studied in 0.1 M HClO₄ containing 10 mM NaCl. Experimental data were shown to be in excellent agreement with theoretical values calculated using the Plieth model. For Pd NPs with 1.0 nm diameter, the oxidation was shifted to less positive potentials by over a third of a volt, representing substantial destabilization of the NP due to its small size.