Abstract
Magnetic resonance electrical impedance tomography (MREIT) utilizes the relation between conductivity and magnetic flux density induced by externally injected current to perform conductivity imaging of body tissues. A spin echo pulse sequence has been predominantly used in MREIT to acquire the z-component Bz of the induced magnetic flux density data from MR phase images. Spin echo based MREIT pulse sequences are most stable and successful in producing high-resolution conductivity images in postmortem and in vivo animal and human experiments. In some applications, localization of a physiological event is desirable. Examples may include detection of neural activities through conductivity changes. In such a case, it would be necessary to maximize the sensitivity. In this paper, we suggest using a balanced steady state free precession (b-SSFP) pulse sequence to localize a small conductivity change. The induced magnetic flux density Bz subject to an injection current makes an off-resonance phase in b-SSFP signals. We expect the high sensitivity of b-SSFP signals to any off-resonance phase change will be advantageous for detecting a small conductivity change. Using computer simulations, we show the feasibility of functional or time-difference MREIT using the b-SSFP pulse sequence.
Original language | English (US) |
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Article number | 012019 |
Journal | Journal of Physics: Conference Series |
Volume | 224 |
Issue number | 1 |
DOIs | |
State | Published - 2010 |
Externally published | Yes |
Event | 14th International Conference on Electrical Bioimpedance, Held in Conjunction with the 11th Conference on Biomedical Applications of EIT, ICEBI and EIT 2010 - Gainesville, FL, United States Duration: Apr 4 2010 → Apr 8 2010 |
ASJC Scopus subject areas
- Physics and Astronomy(all)