Abstract
Magnetic resonance electrical impedance tomography (MREIT) utilizes the relation between conductivity and magnetic flux density induced by externally injected current to perform conductivity imaging of body tissues. A spin echo pulse sequence has been predominantly used in MREIT to acquire the z-component Bz of the induced magnetic flux density data from MR phase images. Spin echo based MREIT pulse sequences are most stable and successful in producing high-resolution conductivity images in postmortem and in vivo animal and human experiments. In some applications, localization of a physiological event is desirable. Examples may include detection of neural activities through conductivity changes. In such a case, it would be necessary to maximize the sensitivity. In this paper, we suggest using a balanced steady state free precession (b-SSFP) pulse sequence to localize a small conductivity change. The induced magnetic flux density Bz subject to an injection current makes an off-resonance phase in b-SSFP signals. We expect the high sensitivity of b-SSFP signals to any off-resonance phase change will be advantageous for detecting a small conductivity change. Using computer simulations, we show the feasibility of functional or time-difference MREIT using the b-SSFP pulse sequence.
| Original language | English (US) |
|---|---|
| Article number | 012019 |
| Journal | Journal of Physics: Conference Series |
| Volume | 224 |
| Issue number | 1 |
| DOIs | |
| State | Published - 2010 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Physics and Astronomy(all)
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Simulation of MREIT using balanced steady state free precession (b-SSFP) pulse sequence. / Minhas, A. S.; Woo, E. J.; Sadleir, Rosalind.
In: Journal of Physics: Conference Series, Vol. 224, No. 1, 012019, 2010.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Simulation of MREIT using balanced steady state free precession (b-SSFP) pulse sequence
AU - Minhas, A. S.
AU - Woo, E. J.
AU - Sadleir, Rosalind
PY - 2010
Y1 - 2010
N2 - Magnetic resonance electrical impedance tomography (MREIT) utilizes the relation between conductivity and magnetic flux density induced by externally injected current to perform conductivity imaging of body tissues. A spin echo pulse sequence has been predominantly used in MREIT to acquire the z-component Bz of the induced magnetic flux density data from MR phase images. Spin echo based MREIT pulse sequences are most stable and successful in producing high-resolution conductivity images in postmortem and in vivo animal and human experiments. In some applications, localization of a physiological event is desirable. Examples may include detection of neural activities through conductivity changes. In such a case, it would be necessary to maximize the sensitivity. In this paper, we suggest using a balanced steady state free precession (b-SSFP) pulse sequence to localize a small conductivity change. The induced magnetic flux density Bz subject to an injection current makes an off-resonance phase in b-SSFP signals. We expect the high sensitivity of b-SSFP signals to any off-resonance phase change will be advantageous for detecting a small conductivity change. Using computer simulations, we show the feasibility of functional or time-difference MREIT using the b-SSFP pulse sequence.
AB - Magnetic resonance electrical impedance tomography (MREIT) utilizes the relation between conductivity and magnetic flux density induced by externally injected current to perform conductivity imaging of body tissues. A spin echo pulse sequence has been predominantly used in MREIT to acquire the z-component Bz of the induced magnetic flux density data from MR phase images. Spin echo based MREIT pulse sequences are most stable and successful in producing high-resolution conductivity images in postmortem and in vivo animal and human experiments. In some applications, localization of a physiological event is desirable. Examples may include detection of neural activities through conductivity changes. In such a case, it would be necessary to maximize the sensitivity. In this paper, we suggest using a balanced steady state free precession (b-SSFP) pulse sequence to localize a small conductivity change. The induced magnetic flux density Bz subject to an injection current makes an off-resonance phase in b-SSFP signals. We expect the high sensitivity of b-SSFP signals to any off-resonance phase change will be advantageous for detecting a small conductivity change. Using computer simulations, we show the feasibility of functional or time-difference MREIT using the b-SSFP pulse sequence.
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U2 - 10.1088/1742-6596/224/1/012019
DO - 10.1088/1742-6596/224/1/012019
M3 - Article
AN - SCOPUS:77954670920
VL - 224
JO - Journal of Physics: Conference Series
JF - Journal of Physics: Conference Series
SN - 1742-6588
IS - 1
M1 - 012019
ER -