Simulation of MREIT using balanced steady state free precession (b-SSFP) pulse sequence

A. S. Minhas, E. J. Woo, R. Sadleir

Research output: Contribution to journalConference article

4 Scopus citations

Abstract

Magnetic resonance electrical impedance tomography (MREIT) utilizes the relation between conductivity and magnetic flux density induced by externally injected current to perform conductivity imaging of body tissues. A spin echo pulse sequence has been predominantly used in MREIT to acquire the z-component Bz of the induced magnetic flux density data from MR phase images. Spin echo based MREIT pulse sequences are most stable and successful in producing high-resolution conductivity images in postmortem and in vivo animal and human experiments. In some applications, localization of a physiological event is desirable. Examples may include detection of neural activities through conductivity changes. In such a case, it would be necessary to maximize the sensitivity. In this paper, we suggest using a balanced steady state free precession (b-SSFP) pulse sequence to localize a small conductivity change. The induced magnetic flux density Bz subject to an injection current makes an off-resonance phase in b-SSFP signals. We expect the high sensitivity of b-SSFP signals to any off-resonance phase change will be advantageous for detecting a small conductivity change. Using computer simulations, we show the feasibility of functional or time-difference MREIT using the b-SSFP pulse sequence.

Original languageEnglish (US)
Article number012019
JournalJournal of Physics: Conference Series
Volume224
Issue number1
DOIs
StatePublished - 2010
Event14th International Conference on Electrical Bioimpedance, Held in Conjunction with the 11th Conference on Biomedical Applications of EIT, ICEBI and EIT 2010 - Gainesville, FL, United States
Duration: Apr 4 2010Apr 8 2010

ASJC Scopus subject areas

  • Physics and Astronomy(all)

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