Simulation of field-effect biosensors (BioFETs) for biotin-streptavidin complexes

Thomas Windbacher, Viktor Sverdlov, Siegfried Selberherr, Clemens Heitzinger, Norbert Mauser, Christian Ringhofer

Research output: Chapter in Book/Report/Conference proceedingConference contribution

4 Scopus citations

Abstract

Biologically sensitive field-effect transistors (BioFETs) are a promising technology for detecting pathogens, antigen-antibody complexes, and tumor markers. A BioFET is studied for a biotin-streptavidin complex. Biotin-streptavidin is used in detection and purification of various biomolecules. The link between the Angstrom scale of the chemical reaction and the micrometer scale of the field effect device is realized by homogenized interface conditions.

Original languageEnglish (US)
Title of host publicationPhysics of Semiconductors - 29th International Conference, ICPS 29
Pages507-508
Number of pages2
DOIs
StatePublished - Dec 1 2009
Event29th International Conference on Physics of Semiconductors, ICPS 29 - Rio de Janeiro, Brazil
Duration: Jul 27 2008Aug 1 2008

Publication series

NameAIP Conference Proceedings
Volume1199
ISSN (Print)0094-243X
ISSN (Electronic)1551-7616

Other

Other29th International Conference on Physics of Semiconductors, ICPS 29
CountryBrazil
CityRio de Janeiro
Period7/27/088/1/08

Keywords

  • BioFET
  • Biotin-streptavidin
  • Field-effect biosensor
  • Interface conditions
  • Multi-scale problem
  • Simulation

ASJC Scopus subject areas

  • Physics and Astronomy(all)

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  • Cite this

    Windbacher, T., Sverdlov, V., Selberherr, S., Heitzinger, C., Mauser, N., & Ringhofer, C. (2009). Simulation of field-effect biosensors (BioFETs) for biotin-streptavidin complexes. In Physics of Semiconductors - 29th International Conference, ICPS 29 (pp. 507-508). (AIP Conference Proceedings; Vol. 1199). https://doi.org/10.1063/1.3295530