Simulation of field-effect biosensors (BioFETs)

Thomas Windbacher; Viktor Sverdlov; Siegfried Selberherr; Clemens Heitzinger; Norbert Mauser; Christian Ringhofer

doi:10.1109/SISPAD.2008.4648270

Simulation of field-effect biosensors (BioFETs)

Thomas Windbacher, Viktor Sverdlov, Siegfried Selberherr, Clemens Heitzinger, Norbert Mauser, Christian Ringhofer

Mathematical and Statistical Sciences, School of (SoMSS)

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

7 Scopus citations

Abstract

In this paper a bottom-up approach for modeling field-effect Biosensors (BioFETs) is developed. Starting from the given positions of charged atoms, of a given molecule, the charge and the dipole moment of a single molecule are calculated. This charge and dipole moment are used to calculate the mean surface density and mean dipole moment at the biofunctionalized surface, which areintroduced into homogenized interface conditions linking the Angstrom-scale of the molecule with the micrometer-scale of the FET. By considering a single-stranded to double-stranded DNA reaction, we demonstrate the capability of a BioFET to detect a certain DNA and to resolve the DNA orientation.

Original language	English (US)
Title of host publication	International Conference on Simulation of Semiconductor Processes and Devices, SISPAD
Pages	193-196
Number of pages	4
DOIs	https://doi.org/10.1109/SISPAD.2008.4648270
State	Published - 2008
Event	2008 International Conference on Simulation of Semiconductor Processes and Devices, SISPAD 2008 - Hakone, Japan Duration: Sep 9 2008 → Sep 11 2008

Other

Other	2008 International Conference on Simulation of Semiconductor Processes and Devices, SISPAD 2008
Country/Territory	Japan
City	Hakone
Period	9/9/08 → 9/11/08

ASJC Scopus subject areas

Electrical and Electronic Engineering
Computer Science Applications
Modeling and Simulation

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10.1109/SISPAD.2008.4648270

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Windbacher, T, Sverdlov, V, Selberherr, S, Heitzinger, C, Mauser, N & Ringhofer, C 2008, Simulation of field-effect biosensors (BioFETs). in International Conference on Simulation of Semiconductor Processes and Devices, SISPAD., 4648270, pp. 193-196, 2008 International Conference on Simulation of Semiconductor Processes and Devices, SISPAD 2008, Hakone, Japan, 9/9/08. https://doi.org/10.1109/SISPAD.2008.4648270

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abstract = "In this paper a bottom-up approach for modeling field-effect Biosensors (BioFETs) is developed. Starting from the given positions of charged atoms, of a given molecule, the charge and the dipole moment of a single molecule are calculated. This charge and dipole moment are used to calculate the mean surface density and mean dipole moment at the biofunctionalized surface, which areintroduced into homogenized interface conditions linking the Angstrom-scale of the molecule with the micrometer-scale of the FET. By considering a single-stranded to double-stranded DNA reaction, we demonstrate the capability of a BioFET to detect a certain DNA and to resolve the DNA orientation.",

author = "Thomas Windbacher and Viktor Sverdlov and Siegfried Selberherr and Clemens Heitzinger and Norbert Mauser and Christian Ringhofer",

year = "2008",

doi = "10.1109/SISPAD.2008.4648270",

language = "English (US)",

pages = "193--196",

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AU - Windbacher, Thomas

AU - Sverdlov, Viktor

AU - Selberherr, Siegfried

AU - Heitzinger, Clemens

AU - Mauser, Norbert

AU - Ringhofer, Christian

PY - 2008

Y1 - 2008

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AB - In this paper a bottom-up approach for modeling field-effect Biosensors (BioFETs) is developed. Starting from the given positions of charged atoms, of a given molecule, the charge and the dipole moment of a single molecule are calculated. This charge and dipole moment are used to calculate the mean surface density and mean dipole moment at the biofunctionalized surface, which areintroduced into homogenized interface conditions linking the Angstrom-scale of the molecule with the micrometer-scale of the FET. By considering a single-stranded to double-stranded DNA reaction, we demonstrate the capability of a BioFET to detect a certain DNA and to resolve the DNA orientation.

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DO - 10.1109/SISPAD.2008.4648270

M3 - Conference contribution

AN - SCOPUS:67650369704

SP - 193

EP - 196

BT - International Conference on Simulation of Semiconductor Processes and Devices, SISPAD

T2 - 2008 International Conference on Simulation of Semiconductor Processes and Devices, SISPAD 2008

Y2 - 9 September 2008 through 11 September 2008

ER -

Simulation of field-effect biosensors (BioFETs)

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