Signaling Endosomes Trigger Synapse Assembly

Jason M. Newbern, Xiaoyan Li, William D. Snider

Research output: Contribution to journalShort survey

1 Scopus citations

Abstract

In this issue of Neuron, Sharma et al. report that target-derived NGF exerts long-distance control of postsynaptic assembly. A major advance is the discovery that TrkA signaling endosomes are retrogradely transported to neuronal dendrites and directly trigger the clustering of postsynaptic density proteins.

Original languageEnglish (US)
Pages (from-to)352-354
Number of pages3
JournalNeuron
Volume67
Issue number3
DOIs
StatePublished - Aug 1 2010

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ASJC Scopus subject areas

  • Neuroscience(all)

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