Sequential processing deficit as a shared persisting biomarker in dyslexia and childhood apraxia of speech

Beate Peter, Hope Lancaster, Caitlin Vose, Kyle Middleton, Carol Stoel-Gammon

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

The purpose of this study was to investigate the hypothesis that individuals with dyslexia and individuals with childhood apraxia of speech share an underlying persisting deficit in processing sequential information. Levels of impairment (sensory encoding, memory, retrieval, and motor planning/programming) were also investigated. Participants were 22 adults with dyslexia, 10 adults with a probable history of childhood apraxia of speech (phCAS), and 22 typical controls. All participants completed nonword repetition, multisyllabic real word repetition, and nonword decoding tasks. Using phonological process analysis, errors were classified as sequence or substitution errors. Adults with dyslexia and adults with phCAS showed evidence of persisting nonword repetition deficits. In all three tasks, the adults in the two disorder groups produced more errors of both classes than the controls, but disproportionally more sequencing than substitution errors during the nonword repetition task. During the real word repetition task, the phCAS produced the most sequencing errors, whereas during the nonword decoding task, the dyslexia group produced the most sequencing errors. Performance during multisyllabic motor speech tasks, relative to monosyllabic conditions, was correlated with the sequencing error component during nonword repetition. The results provide evidence for a shared persisting sequential processing deficit in the dyslexia and phCAS groups during linguistic and motor speech tasks. Evidence for impairments in sensory encoding, short-term memory, and motor planning/programming was found in both disorder groups. Future studies should investigate clinical applications regarding preventative and targeted interventions towards cross-modal treatment effects.

Original languageEnglish (US)
Pages (from-to)1-31
Number of pages31
JournalClinical Linguistics and Phonetics
DOIs
StateAccepted/In press - Sep 20 2017

Fingerprint

Apraxias
Dyslexia
dyslexia
deficit
Biomarkers
childhood
substitution
Group
programming
evidence
process analysis
planning
Linguistics
Childhood Apraxia of Speech
Automatic Data Processing
Short-Term Memory
Nonword Repetition
Sequencing
History
linguistics

Keywords

  • Adults
  • phonology
  • reading
  • short-term memory
  • speech motor control

ASJC Scopus subject areas

  • Language and Linguistics
  • Linguistics and Language
  • Speech and Hearing

Cite this

Sequential processing deficit as a shared persisting biomarker in dyslexia and childhood apraxia of speech. / Peter, Beate; Lancaster, Hope; Vose, Caitlin; Middleton, Kyle; Stoel-Gammon, Carol.

In: Clinical Linguistics and Phonetics, 20.09.2017, p. 1-31.

Research output: Contribution to journalArticle

Peter, Beate ; Lancaster, Hope ; Vose, Caitlin ; Middleton, Kyle ; Stoel-Gammon, Carol. / Sequential processing deficit as a shared persisting biomarker in dyslexia and childhood apraxia of speech. In: Clinical Linguistics and Phonetics. 2017 ; pp. 1-31.
@article{8915e3d9403c41899cf9f1e38848ca83,
title = "Sequential processing deficit as a shared persisting biomarker in dyslexia and childhood apraxia of speech",
abstract = "The purpose of this study was to investigate the hypothesis that individuals with dyslexia and individuals with childhood apraxia of speech share an underlying persisting deficit in processing sequential information. Levels of impairment (sensory encoding, memory, retrieval, and motor planning/programming) were also investigated. Participants were 22 adults with dyslexia, 10 adults with a probable history of childhood apraxia of speech (phCAS), and 22 typical controls. All participants completed nonword repetition, multisyllabic real word repetition, and nonword decoding tasks. Using phonological process analysis, errors were classified as sequence or substitution errors. Adults with dyslexia and adults with phCAS showed evidence of persisting nonword repetition deficits. In all three tasks, the adults in the two disorder groups produced more errors of both classes than the controls, but disproportionally more sequencing than substitution errors during the nonword repetition task. During the real word repetition task, the phCAS produced the most sequencing errors, whereas during the nonword decoding task, the dyslexia group produced the most sequencing errors. Performance during multisyllabic motor speech tasks, relative to monosyllabic conditions, was correlated with the sequencing error component during nonword repetition. The results provide evidence for a shared persisting sequential processing deficit in the dyslexia and phCAS groups during linguistic and motor speech tasks. Evidence for impairments in sensory encoding, short-term memory, and motor planning/programming was found in both disorder groups. Future studies should investigate clinical applications regarding preventative and targeted interventions towards cross-modal treatment effects.",
keywords = "Adults, phonology, reading, short-term memory, speech motor control",
author = "Beate Peter and Hope Lancaster and Caitlin Vose and Kyle Middleton and Carol Stoel-Gammon",
year = "2017",
month = "9",
day = "20",
doi = "10.1080/02699206.2017.1375560",
language = "English (US)",
pages = "1--31",
journal = "Clinical Linguistics and Phonetics",
issn = "0269-9206",
publisher = "Informa Healthcare",

}

TY - JOUR

T1 - Sequential processing deficit as a shared persisting biomarker in dyslexia and childhood apraxia of speech

AU - Peter, Beate

AU - Lancaster, Hope

AU - Vose, Caitlin

AU - Middleton, Kyle

AU - Stoel-Gammon, Carol

PY - 2017/9/20

Y1 - 2017/9/20

N2 - The purpose of this study was to investigate the hypothesis that individuals with dyslexia and individuals with childhood apraxia of speech share an underlying persisting deficit in processing sequential information. Levels of impairment (sensory encoding, memory, retrieval, and motor planning/programming) were also investigated. Participants were 22 adults with dyslexia, 10 adults with a probable history of childhood apraxia of speech (phCAS), and 22 typical controls. All participants completed nonword repetition, multisyllabic real word repetition, and nonword decoding tasks. Using phonological process analysis, errors were classified as sequence or substitution errors. Adults with dyslexia and adults with phCAS showed evidence of persisting nonword repetition deficits. In all three tasks, the adults in the two disorder groups produced more errors of both classes than the controls, but disproportionally more sequencing than substitution errors during the nonword repetition task. During the real word repetition task, the phCAS produced the most sequencing errors, whereas during the nonword decoding task, the dyslexia group produced the most sequencing errors. Performance during multisyllabic motor speech tasks, relative to monosyllabic conditions, was correlated with the sequencing error component during nonword repetition. The results provide evidence for a shared persisting sequential processing deficit in the dyslexia and phCAS groups during linguistic and motor speech tasks. Evidence for impairments in sensory encoding, short-term memory, and motor planning/programming was found in both disorder groups. Future studies should investigate clinical applications regarding preventative and targeted interventions towards cross-modal treatment effects.

AB - The purpose of this study was to investigate the hypothesis that individuals with dyslexia and individuals with childhood apraxia of speech share an underlying persisting deficit in processing sequential information. Levels of impairment (sensory encoding, memory, retrieval, and motor planning/programming) were also investigated. Participants were 22 adults with dyslexia, 10 adults with a probable history of childhood apraxia of speech (phCAS), and 22 typical controls. All participants completed nonword repetition, multisyllabic real word repetition, and nonword decoding tasks. Using phonological process analysis, errors were classified as sequence or substitution errors. Adults with dyslexia and adults with phCAS showed evidence of persisting nonword repetition deficits. In all three tasks, the adults in the two disorder groups produced more errors of both classes than the controls, but disproportionally more sequencing than substitution errors during the nonword repetition task. During the real word repetition task, the phCAS produced the most sequencing errors, whereas during the nonword decoding task, the dyslexia group produced the most sequencing errors. Performance during multisyllabic motor speech tasks, relative to monosyllabic conditions, was correlated with the sequencing error component during nonword repetition. The results provide evidence for a shared persisting sequential processing deficit in the dyslexia and phCAS groups during linguistic and motor speech tasks. Evidence for impairments in sensory encoding, short-term memory, and motor planning/programming was found in both disorder groups. Future studies should investigate clinical applications regarding preventative and targeted interventions towards cross-modal treatment effects.

KW - Adults

KW - phonology

KW - reading

KW - short-term memory

KW - speech motor control

UR - http://www.scopus.com/inward/record.url?scp=85029703074&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85029703074&partnerID=8YFLogxK

U2 - 10.1080/02699206.2017.1375560

DO - 10.1080/02699206.2017.1375560

M3 - Article

SP - 1

EP - 31

JO - Clinical Linguistics and Phonetics

JF - Clinical Linguistics and Phonetics

SN - 0269-9206

ER -