Semi-chronic motorized microdrive and control algorithm for autonomously isolating and maintaining optimal extracellular action potentials

Jorge G. Cham, Edward A. Branchaud, Zoran Nenadic, Bradley Greger, Richard A. Andersen, Joel W. Burdick

Research output: Contribution to journalArticle

77 Scopus citations

Abstract

A system was developed that can autonomously position recording electrodes to isolate and maintain optimal quality extracellular signals. The system consists of a novel motorized miniature recording microdrive and a control algorithm. The microdrive was designed for chronic operation and can independently position four glass-coated Pt-Ir electrodes with micrometer precision over a 5-mm range using small (3 mm diam) piezoelectric linear actuators. The autonomous positioning algorithm is designed to detect, align, and cluster action potentials and then command the microdrive to optimize and maintain the neural signal. This system is shown to be capable of autonomous operation in monkey cortical tissue.

Original languageEnglish (US)
Pages (from-to)570-579
Number of pages10
JournalJournal of neurophysiology
Volume93
Issue number1
DOIs
StatePublished - Jan 1 2005
Externally publishedYes

ASJC Scopus subject areas

  • Neuroscience(all)
  • Physiology

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