Self-organization and entropy reduction in a living cell

Paul Davies, Elisabeth Rieper, Jack A. Tuszynski

Research output: Contribution to journalArticle

42 Citations (Scopus)

Abstract

In this paper we discuss the entropy and information aspects of a living cell. Particular attention is paid to the information gain on assembling and maintaining a living state. Numerical estimates of the information and entropy reduction are given and discussed in the context of the cell's metabolic activity. We discuss a solution to an apparent paradox that there is less information content in DNA than in the proteins that are assembled based on the genetic code encrypted in DNA. When energy input required for protein synthesis is accounted for, the paradox is clearly resolved. Finally, differences between biological information and instruction are discussed.

Original languageEnglish (US)
Pages (from-to)1-10
Number of pages10
JournalBioSystems
Volume111
Issue number1
DOIs
StatePublished - Jan 2013

Fingerprint

Entropy
Self-organization
DNA
Cells
Paradox
Genetic Code
Proteins
Cell
Information Gain
Protein Synthesis
Information Content
Protein
Energy
Estimate

Keywords

  • Entropy
  • Genetic code
  • Information theory
  • Shannon information
  • Thermodynamics

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Applied Mathematics
  • Modeling and Simulation
  • Statistics and Probability

Cite this

Self-organization and entropy reduction in a living cell. / Davies, Paul; Rieper, Elisabeth; Tuszynski, Jack A.

In: BioSystems, Vol. 111, No. 1, 01.2013, p. 1-10.

Research output: Contribution to journalArticle

Davies, Paul ; Rieper, Elisabeth ; Tuszynski, Jack A. / Self-organization and entropy reduction in a living cell. In: BioSystems. 2013 ; Vol. 111, No. 1. pp. 1-10.
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