Self-assembled signaling aptamer DNA arrays for protein detection

Chenxiang Lin; Evaldas Katilius; Yan Liu; Junping Zhang; Hao Yan

doi:10.1002/anie.200600438

Self-assembled signaling aptamer DNA arrays for protein detection

Chenxiang Lin, Evaldas Katilius, Yan Liu, Junping Zhang, Hao Yan

Research output: Contribution to journal › Article › peer-review

144 Scopus citations

Abstract

(Chemical Equation Presented) Sticking the tiles: A DNA-tile-directed self-assembly of signaling aptamers into high-density nanoarrays allows subnanomolar detection of protein molecules by using confocal fluorescence microscopy imaging. This water-soluble aptamer microarray provides a novel strategy for developing programmable sensor arrays.

Original language	English (US)
Pages (from-to)	5296-5301
Number of pages	6
Journal	Angewandte Chemie - International Edition
Volume	45
Issue number	32
DOIs	https://doi.org/10.1002/anie.200600438
State	Published - Aug 4 2006

Keywords

DNA arrays
Molecular recognition
Protein detection
Self-assembly
Signaling aptamers

ASJC Scopus subject areas

Catalysis
General Chemistry

Access to Document

10.1002/anie.200600438

Cite this

@article{87c751e1c77c4ceeb561da617ffad744,

title = "Self-assembled signaling aptamer DNA arrays for protein detection",

abstract = "(Chemical Equation Presented) Sticking the tiles: A DNA-tile-directed self-assembly of signaling aptamers into high-density nanoarrays allows subnanomolar detection of protein molecules by using confocal fluorescence microscopy imaging. This water-soluble aptamer microarray provides a novel strategy for developing programmable sensor arrays.",

keywords = "DNA arrays, Molecular recognition, Protein detection, Self-assembly, Signaling aptamers",

author = "Chenxiang Lin and Evaldas Katilius and Yan Liu and Junping Zhang and Hao Yan",

year = "2006",

month = aug,

day = "4",

doi = "10.1002/anie.200600438",

language = "English (US)",

volume = "45",

pages = "5296--5301",

journal = "Angewandte Chemie - International Edition",

issn = "1433-7851",

publisher = "John Wiley and Sons Ltd",

number = "32",

}

TY - JOUR

T1 - Self-assembled signaling aptamer DNA arrays for protein detection

AU - Lin, Chenxiang

AU - Katilius, Evaldas

AU - Liu, Yan

AU - Zhang, Junping

AU - Yan, Hao

PY - 2006/8/4

Y1 - 2006/8/4

N2 - (Chemical Equation Presented) Sticking the tiles: A DNA-tile-directed self-assembly of signaling aptamers into high-density nanoarrays allows subnanomolar detection of protein molecules by using confocal fluorescence microscopy imaging. This water-soluble aptamer microarray provides a novel strategy for developing programmable sensor arrays.

AB - (Chemical Equation Presented) Sticking the tiles: A DNA-tile-directed self-assembly of signaling aptamers into high-density nanoarrays allows subnanomolar detection of protein molecules by using confocal fluorescence microscopy imaging. This water-soluble aptamer microarray provides a novel strategy for developing programmable sensor arrays.

KW - DNA arrays

KW - Molecular recognition

KW - Protein detection

KW - Self-assembly

KW - Signaling aptamers

UR - http://www.scopus.com/inward/record.url?scp=33747893739&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33747893739&partnerID=8YFLogxK

U2 - 10.1002/anie.200600438

DO - 10.1002/anie.200600438

M3 - Article

C2 - 16847867

AN - SCOPUS:33747893739

SN - 1433-7851

VL - 45

SP - 5296

EP - 5301

JO - Angewandte Chemie - International Edition

JF - Angewandte Chemie - International Edition

IS - 32

ER -

Self-assembled signaling aptamer DNA arrays for protein detection

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this