Selective inactivation of human immunodeficiency virus with subpicosecond near-infrared laser pulses

Kong-Thon Tsen, Shaw Wei D Tsen, Chien Fu Hung, T. C. Wu, Juliann G. Kiang

Research output: Contribution to journalArticle

16 Scopus citations


We demonstrate for the first time that human immunodeficiency virus (HIV) can be inactivated by irradiation with subpicosecond near-infrared laser pulses at a moderate laser power density. By comparing the threshold laser power density for the inactivation of HIV with those of human red blood cells and mouse dendritic cells, we conclude that it is plausible to use the ultrashort pulsed laser to selectively inactivate blood-borne pathogens such as HIV while leaving sensitive materials like human red blood cells unharmed. This finding has important implications in the development of a new laser technology for disinfection of viral pathogens in blood products and in the clinic.

Original languageEnglish (US)
Article number252205
JournalJournal of Physics Condensed Matter
Issue number25
StatePublished - Jun 25 2008


ASJC Scopus subject areas

  • Materials Science(all)
  • Condensed Matter Physics

Cite this