Sedimentation velocity experiments show that only monomers coexist with amyloid fibrils of human islet amyloidpolypeptide. No oligomers containing >100 monomers could be detected, suggesting that the putative toxic oligomers are much larger than those found for the Alzheimer's peptide, Aβ(1-42).
|Original language||English (US)|
|State||Published - Apr 2008|
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