Scalable collaborative infrastructure for a learning healthcare system (SCILHS): Architecture

Kenneth D. Mandl, Isaac S. Kohane, Douglas McFadden, Griffin M. Weber, Marc Natter, Joshua Mandel, Sebastian Schneeweiss, Sarah Weiler, Jeffrey G. Klann, Jonathan Bickel, William G. Adams, Yaorong Ge, Xiaobo Zhou, James Perkins, Keith Marsolo, Elmer Berns tam, John Showalter, Alexander Quarshie, Elizabeth Ofili, George HripcsakShawn N. Murphy

Research output: Contribution to journalArticle

41 Citations (Scopus)

Abstract

We describe the architecture of the Patient Centered Outcomes Research Institute (PCORI) funded Scalable Collaborative Infrastructure for a Learning Healthcare System (SCILHS, http://www.SCILHS.org) clinical data research network, which leverages the $48 billion dollar federal investment in health information technology (IT) to enable a queryable semantic data model across 10 health systems covering more than 8 million patients, plugging universally into the point of care, generating evidence and discovery, and thereby enabling clinician and patient participation in research during the patient encounter. Central to the success of SCILHS is development of innovative 'apps' to improve PCOR research methods and capacitate point of care functions such as consent, enrollment, randomization, and outreach for patient-reported outcomes. SCILHS adapts and extends an existing national research network formed on an advanced IT infrastructure built with open source, free, modular components.

Original languageEnglish (US)
Pages (from-to)615-620
Number of pages6
JournalJournal of the American Medical Informatics Association
Volume21
Issue number4
DOIs
StatePublished - Jan 1 2014
Externally publishedYes

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Learning
Delivery of Health Care
Point-of-Care Systems
Research
Patient Outcome Assessment
Patient Participation
Medical Informatics
Random Allocation
Semantics
Technology
Health

ASJC Scopus subject areas

  • Health Informatics

Cite this

Scalable collaborative infrastructure for a learning healthcare system (SCILHS) : Architecture. / Mandl, Kenneth D.; Kohane, Isaac S.; McFadden, Douglas; Weber, Griffin M.; Natter, Marc; Mandel, Joshua; Schneeweiss, Sebastian; Weiler, Sarah; Klann, Jeffrey G.; Bickel, Jonathan; Adams, William G.; Ge, Yaorong; Zhou, Xiaobo; Perkins, James; Marsolo, Keith; Berns tam, Elmer; Showalter, John; Quarshie, Alexander; Ofili, Elizabeth; Hripcsak, George; Murphy, Shawn N.

In: Journal of the American Medical Informatics Association, Vol. 21, No. 4, 01.01.2014, p. 615-620.

Research output: Contribution to journalArticle

Mandl, KD, Kohane, IS, McFadden, D, Weber, GM, Natter, M, Mandel, J, Schneeweiss, S, Weiler, S, Klann, JG, Bickel, J, Adams, WG, Ge, Y, Zhou, X, Perkins, J, Marsolo, K, Berns tam, E, Showalter, J, Quarshie, A, Ofili, E, Hripcsak, G & Murphy, SN 2014, 'Scalable collaborative infrastructure for a learning healthcare system (SCILHS): Architecture', Journal of the American Medical Informatics Association, vol. 21, no. 4, pp. 615-620. https://doi.org/10.1136/amiajnl-2014-002727
Mandl, Kenneth D. ; Kohane, Isaac S. ; McFadden, Douglas ; Weber, Griffin M. ; Natter, Marc ; Mandel, Joshua ; Schneeweiss, Sebastian ; Weiler, Sarah ; Klann, Jeffrey G. ; Bickel, Jonathan ; Adams, William G. ; Ge, Yaorong ; Zhou, Xiaobo ; Perkins, James ; Marsolo, Keith ; Berns tam, Elmer ; Showalter, John ; Quarshie, Alexander ; Ofili, Elizabeth ; Hripcsak, George ; Murphy, Shawn N. / Scalable collaborative infrastructure for a learning healthcare system (SCILHS) : Architecture. In: Journal of the American Medical Informatics Association. 2014 ; Vol. 21, No. 4. pp. 615-620.
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