Role of the endogenous opioid system on the neuropsychopharmacological effects of ethanol: New insights about an old question

Carles Sanchis-Segura, Judy E. Grisel, M. Foster Olive, Sandra Ghozland, George F. Koob, Amanda J. Roberts, Michael S. Cowen

Research output: Contribution to journalArticle

32 Scopus citations


This article presents the proceedings of the symposium "Endogenous Opioids and Voluntary Ethanol Consumption: What Have We Learnt From Knock-out Mice?" presented at the meeting of the International Society for Biomedical Research on Alcoholism held in Heidelberg/Mannheim, Germany, in September/October 2004. The organizers and chairpersons were Michael S. Cowen and Carles Sanchis-Segura. The presentations were as follows: (1) Regulation of the Opioid System by Alcohol: Comparison of Alcohol-Preferring and -Nonpreferring Strains by Michael S. Cowen; (2) Endogenous Opioids and Alcohol: Lessons From Microdialysis and Knock-out Mice by M. Foster Olive; (3) From Neurochemistry to Neuroanatomy: The Hypothalamic Arcuate Nucleus as a Main Site for Ethanol-Opioids Interaction by Carles Sanchis-Segura; (4) Sensitivity to Ethanol Is Modulated by β-Endorphin in Transgenic Mice by Judy E. Grisel, Amanda J. Roberts, and George F. Koob; and (5) The μ-Opioid Receptor Modulates Acute Ethanol Sensitivity and Ethanol Withdrawal Severity by Sandra Ghozland.

Original languageEnglish (US)
Pages (from-to)1522-1527
Number of pages6
JournalAlcoholism: Clinical and Experimental Research
Issue number8
StatePublished - Aug 1 2005
Externally publishedYes



  • Endorphins
  • Enkephalins
  • Ethanol
  • Knock-Out Mice
  • Nociceptin
  • Opioids

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Toxicology
  • Psychiatry and Mental health

Cite this