RFLPs and linkage relationships of the human laminin B2 gene

Darryl Nishimura; Kenneth H. Buetow; Yoshihiko Yamada; Jeffrey C. Murray

doi:10.1016/0888-7543(88)90134-6

RFLPs and linkage relationships of the human laminin B2 gene

Darryl Nishimura, Kenneth H. Buetow, Yoshihiko Yamada, Jeffrey C. Murray

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

RFLPs for laminin B2 (LAMB2) are reported. These RFLPs were used to study the linkage relationships of LAMB2 to four other genes on lq: Duffy (FY), renin (REN), decay accelerating factor (DAF), and complement receptor 2 (CR2). Multipoint linkage analysis placed LAMB2 between FY and the cluster including REN, DAF, and CR2. This provides a useful bridging polymorphic marker on lq and establishes significant linkage of LAMB2 to FY (θ = 0.23, z = 3.85) and REN (θ = 0.17, z = 4.88).

Original language	English (US)
Pages (from-to)	393-395
Number of pages	3
Journal	Genomics
Volume	3
Issue number	4
DOIs	https://doi.org/10.1016/0888-7543(88)90134-6
State	Published - Nov 1988
Externally published	Yes

ASJC Scopus subject areas

Genetics

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@article{4ef44ec6cb3c4ccd923d5eb88eb27688,

title = "RFLPs and linkage relationships of the human laminin B2 gene",

abstract = "RFLPs for laminin B2 (LAMB2) are reported. These RFLPs were used to study the linkage relationships of LAMB2 to four other genes on lq: Duffy (FY), renin (REN), decay accelerating factor (DAF), and complement receptor 2 (CR2). Multipoint linkage analysis placed LAMB2 between FY and the cluster including REN, DAF, and CR2. This provides a useful bridging polymorphic marker on lq and establishes significant linkage of LAMB2 to FY (θ = 0.23, z = 3.85) and REN (θ = 0.17, z = 4.88).",

author = "Darryl Nishimura and Buetow, {Kenneth H.} and Yoshihiko Yamada and Murray, {Jeffrey C.}",

note = "Funding Information: This work was supported by NIH Grants T32 GM07091 (D.N.) and HD20998 (J.C.M.). We thank I. Caras of Genentech for her gift of the DAF probe and CEPH for DNA samples and software.",

year = "1988",

month = nov,

doi = "10.1016/0888-7543(88)90134-6",

language = "English (US)",

volume = "3",

pages = "393--395",

journal = "Genomics",

issn = "0888-7543",

publisher = "Academic Press Inc.",

number = "4",

}

TY - JOUR

T1 - RFLPs and linkage relationships of the human laminin B2 gene

AU - Nishimura, Darryl

AU - Buetow, Kenneth H.

AU - Yamada, Yoshihiko

AU - Murray, Jeffrey C.

N1 - Funding Information: This work was supported by NIH Grants T32 GM07091 (D.N.) and HD20998 (J.C.M.). We thank I. Caras of Genentech for her gift of the DAF probe and CEPH for DNA samples and software.

PY - 1988/11

Y1 - 1988/11

N2 - RFLPs for laminin B2 (LAMB2) are reported. These RFLPs were used to study the linkage relationships of LAMB2 to four other genes on lq: Duffy (FY), renin (REN), decay accelerating factor (DAF), and complement receptor 2 (CR2). Multipoint linkage analysis placed LAMB2 between FY and the cluster including REN, DAF, and CR2. This provides a useful bridging polymorphic marker on lq and establishes significant linkage of LAMB2 to FY (θ = 0.23, z = 3.85) and REN (θ = 0.17, z = 4.88).

AB - RFLPs for laminin B2 (LAMB2) are reported. These RFLPs were used to study the linkage relationships of LAMB2 to four other genes on lq: Duffy (FY), renin (REN), decay accelerating factor (DAF), and complement receptor 2 (CR2). Multipoint linkage analysis placed LAMB2 between FY and the cluster including REN, DAF, and CR2. This provides a useful bridging polymorphic marker on lq and establishes significant linkage of LAMB2 to FY (θ = 0.23, z = 3.85) and REN (θ = 0.17, z = 4.88).

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EP - 395

JO - Genomics

JF - Genomics

IS - 4

ER -

RFLPs and linkage relationships of the human laminin B2 gene

Abstract

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