Reversible control of biomaterial properties for dynamically tuning cell behavior

Fallon M. Fumasi, Nicholas Stephanopoulos, Julianne L. Holloway

Research output: Contribution to journalArticle

Abstract

In the past decade, significant advances in chemistry and manufacturing have enabled the development of increasingly complex and controllable biomaterials. A key innovation is the design of dynamic biomaterials that allow for user-specified, reversible, temporal control over material properties. In this review, we provide an overview of recent advancements in reversible biomaterials, including control of stiffness, chemistry, ligand presentation, and topography. These systems have wide-ranging applications within biomedical engineering, including in vitro disease models and tissue-engineered scaffolds to guide multistep biological processes.

Original languageEnglish (US)
Article number49058
JournalJournal of Applied Polymer Science
Volume137
Issue number25
DOIs
StateAccepted/In press - Jan 1 2020

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Keywords

  • bioengineering
  • biomedical applications
  • mechanical properties

ASJC Scopus subject areas

  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Polymers and Plastics
  • Materials Chemistry

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