Rescue of vaccinia virus lacking the E3L gene by mutants of E3L

H. W. Chang, L. H. Uribe, Bertram Jacobs

Research output: Contribution to journalArticle

95 Scopus citations

Abstract

Vaccinia virus with the E3L gene deleted was able to replicate in RK-13 but not HeLa cells. This host range phenotype could be complemented by an E3L gene expressed transiently from a plasmid. Analysis of mutants of E3L indicates that the ability to complement deletion of E3L correlates with the ability of mutated proteins to bind double-stranded RNA but not with their ability to migrate to the nucleus.

Original languageEnglish (US)
Pages (from-to)6605-6608
Number of pages4
JournalJournal of virology
Volume69
Issue number10
DOIs
StatePublished - Oct 1995

ASJC Scopus subject areas

  • Microbiology
  • Immunology
  • Insect Science
  • Virology

Fingerprint Dive into the research topics of 'Rescue of vaccinia virus lacking the E3L gene by mutants of E3L'. Together they form a unique fingerprint.

  • Cite this