Reported isolated pancreas rejection is associated with poor kidney outcomes in recipients of a simultaneous pancreas kidney transplant

Bruce Kaplan, Patricia West-Thielke, Heather Herren, John Gill, Greg A. Knoll, Jose Oberholzer, Howard Sankary, Enrico Benedetti

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

BACKGROUND.: We hypothesized that many reported and presumed isolated pancreas acute rejection episodes in simultaneous pancreas kidney patients may in fact be missed concordant kidney acute rejection episodes. METHODS.: To test this hypothesis, we undertook an analysis of the Organ Procurement and Transplant Network database from 1995 to 2006 to assess the impact of reported isolated pancreas rejection on kidney allograft outcomes. The primary outcome of interest was kidney graft status beyond the first posttransplant year. RESULTS.: For overall graft survival, we found that when pancreas alone rejection was compared with no rejection there was a significant difference between the curves (log-rank P

Original languageEnglish (US)
Pages (from-to)1229-1233
Number of pages5
JournalTransplantation
Volume86
Issue number9
DOIs
StatePublished - Nov 15 2008
Externally publishedYes

Fingerprint

Pancreas
Transplants
Kidney
Tissue and Organ Procurement
Graft Survival
Allografts
Databases

Keywords

  • Acute rejection
  • Graft
  • Simultaneous pancreas kidney transplant
  • Survival

ASJC Scopus subject areas

  • Transplantation

Cite this

Kaplan, B., West-Thielke, P., Herren, H., Gill, J., Knoll, G. A., Oberholzer, J., ... Benedetti, E. (2008). Reported isolated pancreas rejection is associated with poor kidney outcomes in recipients of a simultaneous pancreas kidney transplant. Transplantation, 86(9), 1229-1233. https://doi.org/10.1097/TP.0b013e318188ad11

Reported isolated pancreas rejection is associated with poor kidney outcomes in recipients of a simultaneous pancreas kidney transplant. / Kaplan, Bruce; West-Thielke, Patricia; Herren, Heather; Gill, John; Knoll, Greg A.; Oberholzer, Jose; Sankary, Howard; Benedetti, Enrico.

In: Transplantation, Vol. 86, No. 9, 15.11.2008, p. 1229-1233.

Research output: Contribution to journalArticle

Kaplan, B, West-Thielke, P, Herren, H, Gill, J, Knoll, GA, Oberholzer, J, Sankary, H & Benedetti, E 2008, 'Reported isolated pancreas rejection is associated with poor kidney outcomes in recipients of a simultaneous pancreas kidney transplant', Transplantation, vol. 86, no. 9, pp. 1229-1233. https://doi.org/10.1097/TP.0b013e318188ad11
Kaplan, Bruce ; West-Thielke, Patricia ; Herren, Heather ; Gill, John ; Knoll, Greg A. ; Oberholzer, Jose ; Sankary, Howard ; Benedetti, Enrico. / Reported isolated pancreas rejection is associated with poor kidney outcomes in recipients of a simultaneous pancreas kidney transplant. In: Transplantation. 2008 ; Vol. 86, No. 9. pp. 1229-1233.
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