Reovirus Sigma3 Protein as an Inhibitor of the DSRNA-Dependent Protein Kinase

Bertram Jacobs (Inventor)

Research output: Patent

Abstract

The reoviras Sigma3 protein can function as an inhibitor of the dsRNA-dependent protein Kinase. Since the dsRNA-dependent protein Kinase can inhibit expression in mammalian cells of genetically engineered DNA the Sigma3 protein can lead to significant increases in expression of cloned genes.
Original languageEnglish (US)
StatePublished - Jan 1 1900

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Protein Kinases
Proteins
Gene Expression
DNA

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title = "Reovirus Sigma3 Protein as an Inhibitor of the DSRNA-Dependent Protein Kinase",
abstract = "The reoviras Sigma3 protein can function as an inhibitor of the dsRNA-dependent protein Kinase. Since the dsRNA-dependent protein Kinase can inhibit expression in mammalian cells of genetically engineered DNA the Sigma3 protein can lead to significant increases in expression of cloned genes.",
author = "Bertram Jacobs",
year = "1900",
month = "1",
day = "1",
language = "English (US)",
type = "Patent",

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AB - The reoviras Sigma3 protein can function as an inhibitor of the dsRNA-dependent protein Kinase. Since the dsRNA-dependent protein Kinase can inhibit expression in mammalian cells of genetically engineered DNA the Sigma3 protein can lead to significant increases in expression of cloned genes.

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