Reovirus Sigma3 Protein as an Inhibitor of the DSRNA-Dependent Protein Kinase

Bertram Jacobs (Inventor)

Research output: Patent


The reoviras Sigma3 protein can function as an inhibitor of the dsRNA-dependent protein Kinase. Since the dsRNA-dependent protein Kinase can inhibit expression in mammalian cells of genetically engineered DNA the Sigma3 protein can lead to significant increases in expression of cloned genes.
Original languageEnglish (US)
StatePublished - Jan 1 1900


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