Reimagining C(sp3)–N bond formation via a HARC strategy

Michael S. Crocker, Reem Nsouli, Laura K.G. Ackerman-Biegasiewicz

Research output: Contribution to journalArticlepeer-review

Abstract

Conventional N-alkylation methods have been limited to approaches with high energy barriers and low selectivity. In this issue of Chem, MacMillan and co-workers report an innovative halogen abstraction-radical capture (HARC) strategy via metallaphotoredox catalysis that couples strained and hindered alkyl halides with a diverse range of N-nucleophiles.

Original languageEnglish (US)
Pages (from-to)1688-1691
Number of pages4
JournalChem
Volume7
Issue number7
DOIs
StatePublished - Jul 8 2021
Externally publishedYes

ASJC Scopus subject areas

  • Chemistry(all)
  • Biochemistry
  • Environmental Chemistry
  • Chemical Engineering(all)
  • Biochemistry, medical
  • Materials Chemistry

Fingerprint

Dive into the research topics of 'Reimagining C(sp3)–N bond formation via a HARC strategy'. Together they form a unique fingerprint.

Cite this