Red cell superoxide dismutase is increased in iron deficiency anemia

Lennart T. Jansson, Mikko V. Perkkiö, Wayne T. Willis, Canio J. Refino, Peter R. Dallman

Research output: Contribution to journalArticle

38 Scopus citations

Abstract

Red blood cells (RBC) from iron-deficient rats were found to generate more malonyldialdehyde after in vitro incubation with H2O2 than RBC from control rats (p < 0.001). The iron-deficient RBC, however, had a higher content of superoxide dismutase (SOD) than control RBC (p < 0.02). This finding suggests an increased formation of SOD compensatory to an increased oxidant stress.

Original languageEnglish (US)
Pages (from-to)218-221
Number of pages4
JournalActa Haematologica
Volume74
Issue number4
DOIs
StatePublished - Jan 1 1985

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Keywords

  • Anemia
  • Iron deficiency
  • Superoxide dismutase

ASJC Scopus subject areas

  • Hematology

Cite this

Jansson, L. T., Perkkiö, M. V., Willis, W. T., Refino, C. J., & Dallman, P. R. (1985). Red cell superoxide dismutase is increased in iron deficiency anemia. Acta Haematologica, 74(4), 218-221. https://doi.org/10.1159/000206222