Recent developments in emerging microimmunoassays

Christine F. Woolley, Mark Hayes

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Creative and novel microimmunoassay approaches continue to proliferate across many platforms originating from several fields of study. These efforts are aimed at improving one or more metrics for clinical tests, including improved sensitivity, increased speed, reduced cost, smaller sample size, the ability to analyze multiple antigens in parallel and ease of use. Many approaches focus on the production of microarrays that accomplish standard assays in parallel, or mobile solid-support formats to overcome issues of high background noise and long incubation times. In this article, innovative developments beyond existing commercial tests in the microimmunoassay arena are reviewed, covering January 2008 to April 2012. These developing experimental platforms are discussed in terms of their ability to augment or replace current commercial approaches.

Original languageEnglish (US)
Pages (from-to)245-264
Number of pages20
JournalBioanalysis
Volume5
Issue number2
DOIs
StatePublished - Jan 2013

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Microarrays
Sample Size
Noise
Assays
Antigens
Costs and Cost Analysis
Costs

ASJC Scopus subject areas

  • Clinical Biochemistry
  • Pharmacology, Toxicology and Pharmaceutics(all)
  • Medical Laboratory Technology
  • Analytical Chemistry

Cite this

Recent developments in emerging microimmunoassays. / Woolley, Christine F.; Hayes, Mark.

In: Bioanalysis, Vol. 5, No. 2, 01.2013, p. 245-264.

Research output: Contribution to journalArticle

Woolley, Christine F. ; Hayes, Mark. / Recent developments in emerging microimmunoassays. In: Bioanalysis. 2013 ; Vol. 5, No. 2. pp. 245-264.
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