Real-time interaction between a neuromorphic electronic circuit and the spinal cord

Ranu Jung; Elizabeth J. Brauer; James J. Abbas

doi:10.1109/7333.948461

Real-time interaction between a neuromorphic electronic circuit and the spinal cord

Ranu Jung, Elizabeth J. Brauer, James J. Abbas

Research output: Contribution to journal › Article › peer-review

54 Scopus citations

Abstract

We present a novel demonstration of real-time dynamic interaction between an oscillatory spinal cord (isolated lamprey nervous system) and electronic hardware that mimics the spinal motor pattern generating circuitry. The spinal cord and the neuromorphic circuit were interfaced in unidirectional and bidirectional modes. Bidirectional coupling resulted in stable, persistent oscillations. This experimental platform offers a unique paradigm to examine the intrinsic dynamics of neural circuitry. The neuromorphic analog very large scale integration (aVLSI) design and real-time capabilities of this approach may provide a particularly powerful means of restoring complex neuromotor function using neuroprostheses.

Original language	English (US)
Pages (from-to)	319-326
Number of pages	8
Journal	IEEE Transactions on Neural Systems and Rehabilitation Engineering
Volume	9
Issue number	3
DOIs	https://doi.org/10.1109/7333.948461
State	Published - 2001
Externally published	Yes

Keywords

Analog very large scale integration (aVLSI)
Lamprey
Locomotor control
Neural engineering
Neuromorphic design
Neuroprostheses
Pattern generator
Spinal cord

ASJC Scopus subject areas

General Neuroscience
Biomedical Engineering
Computer Science Applications

Access to Document

10.1109/7333.948461

Cite this

@article{e2772c3db3bb4498adb8c84ec1e3b009,

title = "Real-time interaction between a neuromorphic electronic circuit and the spinal cord",

abstract = "We present a novel demonstration of real-time dynamic interaction between an oscillatory spinal cord (isolated lamprey nervous system) and electronic hardware that mimics the spinal motor pattern generating circuitry. The spinal cord and the neuromorphic circuit were interfaced in unidirectional and bidirectional modes. Bidirectional coupling resulted in stable, persistent oscillations. This experimental platform offers a unique paradigm to examine the intrinsic dynamics of neural circuitry. The neuromorphic analog very large scale integration (aVLSI) design and real-time capabilities of this approach may provide a particularly powerful means of restoring complex neuromotor function using neuroprostheses.",

keywords = "Analog very large scale integration (aVLSI), Lamprey, Locomotor control, Neural engineering, Neuromorphic design, Neuroprostheses, Pattern generator, Spinal cord",

author = "Ranu Jung and Brauer, {Elizabeth J.} and Abbas, {James J.}",

note = "Funding Information: Manuscript received December 18, 2000; revised April 25, 2001 and May 11, 2001. This work was supported by the NIH under Grant RR12588. R. Jung is with the Center for Biomedical Engineering, Department of Electrical and Computer Engineering, and Spinal Cord and Brain Injury Research Center, University of Kentucky, Lexington, KY 40506-0070 USA (e-mail: jung@uky.edu). E. J. Brauer is with the Department of Computer Science and Electrical Engineering, Northern Arizona University, Flagstaff, AZ 86011-5600 USA. J. J. Abbas is with the Center for Biomedical Engineering, Department of Physical Medicine and Rehabilitation, and Spinal Cord and Brain Injury Research Center, University of Kentucky, Lexington, KY 40506-0070 USA. Publisher Item Identifier S 1534-4320(01)07305-3.",

year = "2001",

doi = "10.1109/7333.948461",

language = "English (US)",

volume = "9",

pages = "319--326",

journal = "IEEE Transactions on Neural Systems and Rehabilitation Engineering",

issn = "1534-4320",

publisher = "Institute of Electrical and Electronics Engineers Inc.",

number = "3",

}

TY - JOUR

T1 - Real-time interaction between a neuromorphic electronic circuit and the spinal cord

AU - Jung, Ranu

AU - Brauer, Elizabeth J.

AU - Abbas, James J.

N1 - Funding Information: Manuscript received December 18, 2000; revised April 25, 2001 and May 11, 2001. This work was supported by the NIH under Grant RR12588. R. Jung is with the Center for Biomedical Engineering, Department of Electrical and Computer Engineering, and Spinal Cord and Brain Injury Research Center, University of Kentucky, Lexington, KY 40506-0070 USA (e-mail: jung@uky.edu). E. J. Brauer is with the Department of Computer Science and Electrical Engineering, Northern Arizona University, Flagstaff, AZ 86011-5600 USA. J. J. Abbas is with the Center for Biomedical Engineering, Department of Physical Medicine and Rehabilitation, and Spinal Cord and Brain Injury Research Center, University of Kentucky, Lexington, KY 40506-0070 USA. Publisher Item Identifier S 1534-4320(01)07305-3.

PY - 2001

Y1 - 2001

N2 - We present a novel demonstration of real-time dynamic interaction between an oscillatory spinal cord (isolated lamprey nervous system) and electronic hardware that mimics the spinal motor pattern generating circuitry. The spinal cord and the neuromorphic circuit were interfaced in unidirectional and bidirectional modes. Bidirectional coupling resulted in stable, persistent oscillations. This experimental platform offers a unique paradigm to examine the intrinsic dynamics of neural circuitry. The neuromorphic analog very large scale integration (aVLSI) design and real-time capabilities of this approach may provide a particularly powerful means of restoring complex neuromotor function using neuroprostheses.

AB - We present a novel demonstration of real-time dynamic interaction between an oscillatory spinal cord (isolated lamprey nervous system) and electronic hardware that mimics the spinal motor pattern generating circuitry. The spinal cord and the neuromorphic circuit were interfaced in unidirectional and bidirectional modes. Bidirectional coupling resulted in stable, persistent oscillations. This experimental platform offers a unique paradigm to examine the intrinsic dynamics of neural circuitry. The neuromorphic analog very large scale integration (aVLSI) design and real-time capabilities of this approach may provide a particularly powerful means of restoring complex neuromotor function using neuroprostheses.

KW - Analog very large scale integration (aVLSI)

KW - Lamprey

KW - Locomotor control

KW - Neural engineering

KW - Neuromorphic design

KW - Neuroprostheses

KW - Pattern generator

KW - Spinal cord

UR - http://www.scopus.com/inward/record.url?scp=0034836554&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0034836554&partnerID=8YFLogxK

U2 - 10.1109/7333.948461

DO - 10.1109/7333.948461

M3 - Article

C2 - 11561669

AN - SCOPUS:0034836554

SN - 1534-4320

VL - 9

SP - 319

EP - 326

JO - IEEE Transactions on Neural Systems and Rehabilitation Engineering

JF - IEEE Transactions on Neural Systems and Rehabilitation Engineering

IS - 3

ER -

Real-time interaction between a neuromorphic electronic circuit and the spinal cord

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this