Real-Time analysis of exosome secretion of single cells with single molecule imaging

Pengfei Zhang, Shaopeng Wang

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

The exosome-mediated response can promote or restrain the diseases by regulating the intracellular pathways, making the exosome become an effective marker for diagnosis and therapeutic control at the single-cell level. However, real-Time analysis is hard to be achieved with traditional approaches because the exosomes usually need to be enriched by ultracentrifugation for a measurable signal-To-noise ratio. Recently developed label-free single-molecule imaging approaches may become an real-Time quantitative tool for the analysis of single exosomes and related secretion behaviors of single living cells owing to their extreme sensitivity.

Original languageEnglish (US)
Pages (from-to)1449-1451
Number of pages3
JournalBiocell
Volume45
Issue number6
DOIs
StatePublished - 2021

Keywords

  • Cell secretion
  • Label-free
  • Plasmonic scattering
  • Single molecule imaging

ASJC Scopus subject areas

  • Cell Biology

Fingerprint

Dive into the research topics of 'Real-Time analysis of exosome secretion of single cells with single molecule imaging'. Together they form a unique fingerprint.

Cite this