Abstract
The exosome-mediated response can promote or restrain the diseases by regulating the intracellular pathways, making the exosome become an effective marker for diagnosis and therapeutic control at the single-cell level. However, real-Time analysis is hard to be achieved with traditional approaches because the exosomes usually need to be enriched by ultracentrifugation for a measurable signal-To-noise ratio. Recently developed label-free single-molecule imaging approaches may become an real-Time quantitative tool for the analysis of single exosomes and related secretion behaviors of single living cells owing to their extreme sensitivity.
Original language | English (US) |
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Pages (from-to) | 1449-1451 |
Number of pages | 3 |
Journal | Biocell |
Volume | 45 |
Issue number | 6 |
DOIs | |
State | Published - 2021 |
Keywords
- Cell secretion
- Label-free
- Plasmonic scattering
- Single molecule imaging
ASJC Scopus subject areas
- Cell Biology