Rationale, design, and development of SleepWell24: A smartphone application to promote adherence to positive airway pressure therapy among patients with obstructive sleep apnea

Megan E. Petrov, Kristina Hasanaj, Coles M. Hoffmann, Dana R. Epstein, Lois Krahn, John G. Park, Kevin Hollingshead, Tsung Yen Yu, Michael Todd, Erik K. St. Louis, Timothy I. Morgenthaler, Matthew P. Buman

Research output: Contribution to journalArticle

Abstract

Background: Positive airway pressure (PAP) therapy is the gold standard treatment for obstructive sleep apnea (OSA), a chronic disorder that affects 6–13% of the adult population. However, adherence to PAP therapy is challenging, and current approaches to improve adherence have limited efficacy and scalability. Methods/design: To promote PAP adherence, we developed SleepWell24, a multicomponent, evidence-based smartphone application that delivers objective biofeedback concerning PAP use and sleep/physical activity patterns via cloud-based PAP machine and wearable sensor data, and behavior change strategies and troubleshooting of PAP therapy interface use. This randomized controlled trial will evaluate the feasibility, acceptability, and initial efficacy of SleepWell24 compared to a usual care control condition during the first 60 days of PAP therapy among patients newly diagnosed with OSA. Discussion: SleepWell24 is an innovative, multi-component behavior change intervention, designed as a self-management approach to addressing the psychosocial determinants of adherence to PAP therapy among new users. The results will guide lengthier future trials that assess numerous patient-centered and clinical outcomes.

Original languageEnglish (US)
Article number105908
JournalContemporary Clinical Trials
Volume89
DOIs
StatePublished - Feb 2020

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Keywords

  • Mobile health
  • Obstructive sleep apnea
  • Physical activity
  • Sleep
  • Wearable sensors

ASJC Scopus subject areas

  • Pharmacology (medical)

Cite this

Petrov, M. E., Hasanaj, K., Hoffmann, C. M., Epstein, D. R., Krahn, L., Park, J. G., Hollingshead, K., Yu, T. Y., Todd, M., St. Louis, E. K., Morgenthaler, T. I., & Buman, M. P. (2020). Rationale, design, and development of SleepWell24: A smartphone application to promote adherence to positive airway pressure therapy among patients with obstructive sleep apnea. Contemporary Clinical Trials, 89, [105908]. https://doi.org/10.1016/j.cct.2019.105908