Ratiometric glucose sensing based on fluorescent oxygen films and glucose oxidase

Fengyu Su; Liqiang Zhang; Xiangxing Kong; Fred Lee; Yanqing Tian; Deirdre Meldrum

doi:10.1016/j.sbsr.2017.03.004

Ratiometric glucose sensing based on fluorescent oxygen films and glucose oxidase

Fengyu Su, Liqiang Zhang, Xiangxing Kong, Fred Lee, Yanqing Tian, Deirdre Meldrum

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Abstract

A new two-layer sensor film was constructed for sensing glucose based on glucose oxidase and oxygen sensing material. The first layer of film containing the oxygen sensor and intra-reference material was polymerized, then the second layer of glucose oxidase and glutaraldehyde was formed on the oxygen sensor layer. The two-layer sensor film has a resolution up to 0.05 mM and a detection range from 0 to 5 mM to glucose. The effects of pH and temperature on the sensing performance were systematically investigated. The selective detection of glucose among other monosaccharides, such as fructose, mannose and galactose indicated that the sensing film has excellent selectivity. The prepared sensor was successfully applied for glucose sample detection of glucose concentration in artificial tears.

Original language	English (US)
Pages (from-to)	1-6
Number of pages	6
Journal	Sensing and Bio-Sensing Research
Volume	14
DOIs	https://doi.org/10.1016/j.sbsr.2017.03.004
State	Published - Jun 1 2017

Keywords

Diabetes
Fluorescence
Glucose oxidase
Glucose sensor
Oxygen film

ASJC Scopus subject areas

Biotechnology
Electronic, Optical and Magnetic Materials
Signal Processing
Electrical and Electronic Engineering

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10.1016/j.sbsr.2017.03.004

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title = "Ratiometric glucose sensing based on fluorescent oxygen films and glucose oxidase",

abstract = "A new two-layer sensor film was constructed for sensing glucose based on glucose oxidase and oxygen sensing material. The first layer of film containing the oxygen sensor and intra-reference material was polymerized, then the second layer of glucose oxidase and glutaraldehyde was formed on the oxygen sensor layer. The two-layer sensor film has a resolution up to 0.05 mM and a detection range from 0 to 5 mM to glucose. The effects of pH and temperature on the sensing performance were systematically investigated. The selective detection of glucose among other monosaccharides, such as fructose, mannose and galactose indicated that the sensing film has excellent selectivity. The prepared sensor was successfully applied for glucose sample detection of glucose concentration in artificial tears.",

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AU - Su, Fengyu

AU - Zhang, Liqiang

AU - Kong, Xiangxing

AU - Lee, Fred

AU - Tian, Yanqing

AU - Meldrum, Deirdre

PY - 2017/6/1

Y1 - 2017/6/1

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AB - A new two-layer sensor film was constructed for sensing glucose based on glucose oxidase and oxygen sensing material. The first layer of film containing the oxygen sensor and intra-reference material was polymerized, then the second layer of glucose oxidase and glutaraldehyde was formed on the oxygen sensor layer. The two-layer sensor film has a resolution up to 0.05 mM and a detection range from 0 to 5 mM to glucose. The effects of pH and temperature on the sensing performance were systematically investigated. The selective detection of glucose among other monosaccharides, such as fructose, mannose and galactose indicated that the sensing film has excellent selectivity. The prepared sensor was successfully applied for glucose sample detection of glucose concentration in artificial tears.

KW - Diabetes

KW - Fluorescence

KW - Glucose oxidase

KW - Glucose sensor

KW - Oxygen film

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Ratiometric glucose sensing based on fluorescent oxygen films and glucose oxidase

Abstract

Keywords

ASJC Scopus subject areas

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