Question of the Ribosyl Moiety in the Promotion of Callus Growth by Exogenously Added Cytokinins

Sidney M. Hecht; Robert M. Bock; Ruth Y. Schmitz; Folke Skoog; Nelson J. Leonard; John L. Occolowitz

doi:10.1021/bi00799a011

Question of the Ribosyl Moiety in the Promotion of Callus Growth by Exogenously Added Cytokinins

Sidney M. Hecht, Robert M. Bock, Ruth Y. Schmitz, Folke Skoog, Nelson J. Leonard, John L. Occolowitz

Research output: Contribution to journal › Article › peer-review

24 Scopus citations

Abstract

We have examined the role of the 9 position and the influence of the 9-substituents on the cytokinin activity of N⁶-(isopent(en)yl)adenine derivatives. Five new cytokinin analogs have been employed in this study: 7-(3-methyl-2-butenylamino)pyrazolo[4,3-d]pyrimidine, 3-methyl-7-(3-methyl-2-butenylamino)pyrazolo[4,3-d]pyrimidine, 7-(3-methy 1-2- butenylamino)-3-β-D-ribofuranosylpyrazolo[4,3 - d]pyrimidine, 7-(3-methylbutylamino)pyrazolo[4,5 -d]pyrimidine, and 3-methyl-7-(3-methylbutylamino)pyrazolo[4,3-d]pyrimidine. Their activities have been compared with those of the corresponding purine derivatives. The relative biological activities in the tobacco bioassay suggested that the addition of a ribosyl moiety in the 9 position of exogenously supplied cytokinins is not a prerequisite for their promotion of cell division and growth of plant tissue.

Original language	English (US)
Pages (from-to)	4224-4228
Number of pages	5
Journal	Biochemistry
Volume	10
Issue number	23
DOIs	https://doi.org/10.1021/bi00799a011
State	Published - Nov 1 1971
Externally published	Yes

ASJC Scopus subject areas

Biochemistry

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title = "Question of the Ribosyl Moiety in the Promotion of Callus Growth by Exogenously Added Cytokinins",

abstract = "We have examined the role of the 9 position and the influence of the 9-substituents on the cytokinin activity of N6-(isopent(en)yl)adenine derivatives. Five new cytokinin analogs have been employed in this study: 7-(3-methyl-2-butenylamino)pyrazolo[4,3-d]pyrimidine, 3-methyl-7-(3-methyl-2-butenylamino)pyrazolo[4,3-d]pyrimidine, 7-(3-methy 1-2- butenylamino)-3-β-D-ribofuranosylpyrazolo[4,3 - d]pyrimidine, 7-(3-methylbutylamino)pyrazolo[4,5 -d]pyrimidine, and 3-methyl-7-(3-methylbutylamino)pyrazolo[4,3-d]pyrimidine. Their activities have been compared with those of the corresponding purine derivatives. The relative biological activities in the tobacco bioassay suggested that the addition of a ribosyl moiety in the 9 position of exogenously supplied cytokinins is not a prerequisite for their promotion of cell division and growth of plant tissue.",

author = "Hecht, {Sidney M.} and Bock, {Robert M.} and Schmitz, {Ruth Y.} and Folke Skoog and Leonard, {Nelson J.} and Occolowitz, {John L.}",

year = "1971",

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AU - Hecht, Sidney M.

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AU - Skoog, Folke

AU - Leonard, Nelson J.

AU - Occolowitz, John L.

PY - 1971/11/1

Y1 - 1971/11/1

N2 - We have examined the role of the 9 position and the influence of the 9-substituents on the cytokinin activity of N6-(isopent(en)yl)adenine derivatives. Five new cytokinin analogs have been employed in this study: 7-(3-methyl-2-butenylamino)pyrazolo[4,3-d]pyrimidine, 3-methyl-7-(3-methyl-2-butenylamino)pyrazolo[4,3-d]pyrimidine, 7-(3-methy 1-2- butenylamino)-3-β-D-ribofuranosylpyrazolo[4,3 - d]pyrimidine, 7-(3-methylbutylamino)pyrazolo[4,5 -d]pyrimidine, and 3-methyl-7-(3-methylbutylamino)pyrazolo[4,3-d]pyrimidine. Their activities have been compared with those of the corresponding purine derivatives. The relative biological activities in the tobacco bioassay suggested that the addition of a ribosyl moiety in the 9 position of exogenously supplied cytokinins is not a prerequisite for their promotion of cell division and growth of plant tissue.

AB - We have examined the role of the 9 position and the influence of the 9-substituents on the cytokinin activity of N6-(isopent(en)yl)adenine derivatives. Five new cytokinin analogs have been employed in this study: 7-(3-methyl-2-butenylamino)pyrazolo[4,3-d]pyrimidine, 3-methyl-7-(3-methyl-2-butenylamino)pyrazolo[4,3-d]pyrimidine, 7-(3-methy 1-2- butenylamino)-3-β-D-ribofuranosylpyrazolo[4,3 - d]pyrimidine, 7-(3-methylbutylamino)pyrazolo[4,5 -d]pyrimidine, and 3-methyl-7-(3-methylbutylamino)pyrazolo[4,3-d]pyrimidine. Their activities have been compared with those of the corresponding purine derivatives. The relative biological activities in the tobacco bioassay suggested that the addition of a ribosyl moiety in the 9 position of exogenously supplied cytokinins is not a prerequisite for their promotion of cell division and growth of plant tissue.

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Question of the Ribosyl Moiety in the Promotion of Callus Growth by Exogenously Added Cytokinins

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