Pushing back the expansion of introns in animal genomes

Sudhir Kumar; S. Blair Hedges

doi:10.1016/j.cell.2005.12.007

Pushing back the expansion of introns in animal genomes

Sudhir Kumar, S. Blair Hedges

Life Sciences, School of (SOLS)

Research output: Contribution to journal › Short survey › peer-review

Abstract

In a recent paper in Science, Raible et al. (2005) surveyed the position of introns in 30 genes of a marine annelid and showed that over 60% of the introns occupy positions identical to those in human homologs. In contrast, both human and marine annelid genes share only 30% of their introns with other invertebrates. These observations suggest that the common ancestor of most animal phyla had intron-rich genes and reinforce the notion that introns proliferated early in the evolutionary history of eukaryotes.

Original language	English (US)
Pages (from-to)	1182-1184
Number of pages	3
Journal	Cell
Volume	123
Issue number	7
DOIs	https://doi.org/10.1016/j.cell.2005.12.007
State	Published - Dec 29 2005

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)

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10.1016/j.cell.2005.12.007

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AB - In a recent paper in Science, Raible et al. (2005) surveyed the position of introns in 30 genes of a marine annelid and showed that over 60% of the introns occupy positions identical to those in human homologs. In contrast, both human and marine annelid genes share only 30% of their introns with other invertebrates. These observations suggest that the common ancestor of most animal phyla had intron-rich genes and reinforce the notion that introns proliferated early in the evolutionary history of eukaryotes.

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Pushing back the expansion of introns in animal genomes

Abstract

ASJC Scopus subject areas

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