Pulsed-field separation of particles in a microfluidic device

J. Regtmeier, R. Eichhorn, T. T. Duong, P. Reimann, D. Anselmetti, Alexandra Ros

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

We demonstrate the proof-of-principle of a new separation concept for micrometer-sized particles in a structured microfluidic device. Under the action of externally applied, periodic voltage-pulses two different species of like-charged polystyrene beads are observed to simultaneously migrate into opposite directions. Based on a theoretical model of the particle motion in the microdevice that shows good agreement with the experimental measurements, the underlying separation mechanism is identified and explained. Potential biophysical applications, such as cell sorting, are briefly addressed.

Original languageEnglish (US)
Pages (from-to)335-340
Number of pages6
JournalEuropean Physical Journal E
Volume22
Issue number4
DOIs
StatePublished - Apr 2007
Externally publishedYes

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Lab-On-A-Chip Devices
microfluidic devices
Polystyrenes
Microfluidics
Theoretical Models
particle motion
classifying
Sorting
beads
micrometers
polystyrene
Cells
Electric potential
electric potential
pulses
Direction compound

ASJC Scopus subject areas

  • Materials Science(all)
  • Physics and Astronomy (miscellaneous)

Cite this

Regtmeier, J., Eichhorn, R., Duong, T. T., Reimann, P., Anselmetti, D., & Ros, A. (2007). Pulsed-field separation of particles in a microfluidic device. European Physical Journal E, 22(4), 335-340. https://doi.org/10.1140/epje/e2007-00040-y

Pulsed-field separation of particles in a microfluidic device. / Regtmeier, J.; Eichhorn, R.; Duong, T. T.; Reimann, P.; Anselmetti, D.; Ros, Alexandra.

In: European Physical Journal E, Vol. 22, No. 4, 04.2007, p. 335-340.

Research output: Contribution to journalArticle

Regtmeier, J, Eichhorn, R, Duong, TT, Reimann, P, Anselmetti, D & Ros, A 2007, 'Pulsed-field separation of particles in a microfluidic device', European Physical Journal E, vol. 22, no. 4, pp. 335-340. https://doi.org/10.1140/epje/e2007-00040-y
Regtmeier, J. ; Eichhorn, R. ; Duong, T. T. ; Reimann, P. ; Anselmetti, D. ; Ros, Alexandra. / Pulsed-field separation of particles in a microfluidic device. In: European Physical Journal E. 2007 ; Vol. 22, No. 4. pp. 335-340.
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