Public variant databases: Liability?

Adrian Thorogood, Robert Cook-Deegan, Bartha Maria Knoppers

    Research output: Contribution to journalArticlepeer-review

    18 Scopus citations


    Public variant databases support the curation, clinical interpretation, and sharing of genomic data, thus reducing harmful errors or delays in diagnosis. As variant databases are increasingly relied on in the clinical context, there is concern that negligent variant interpretation will harm patients and attract liability. This article explores the evolving legal duties of laboratories, public variant databases, and physicians in clinical genomics and recommends a governance framework for databases to promote responsible data sharing.Genet Med advance online publication 15 December 2016.

    Original languageEnglish (US)
    Pages (from-to)838-841
    Number of pages4
    JournalGenetics in Medicine
    Issue number7
    StatePublished - Jul 1 2017


    • data sharing
    • genomics
    • legal
    • liability
    • variant databases

    ASJC Scopus subject areas

    • Genetics(clinical)


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