TY - JOUR
T1 - Protein Structure Initiative Material Repository
T2 - An open shared public resource of structural genomics plasmids for the biological community
AU - Cormier, Catherine Y.
AU - Mohr, Stephanie E.
AU - Zuo, Dongmei
AU - Hu, Yanhui
AU - Rolfs, Andreas
AU - Kramer, Jason
AU - Taycher, Elena
AU - Kelley, Fontina
AU - Fiacco, Michael
AU - Turnbull, Greggory
AU - LaBaer, Joshua
PY - 2009/11/10
Y1 - 2009/11/10
N2 - The Protein Structure Initiative Material Repository (PSI-MR; http://psimr.asu.edu) provides centralized storage and distribution for the protein expression plasmids created by PSI researchers. These plasmids are a resource that allows the research community to dissect the biological function of proteins whose structures have been identified by the PSI. The plasmid annotation, which includes the full length sequence, vector information and associated publications, is stored in a freely available, searchable database called DNASU (http://dnasu.asu.edu). Each PSI plasmid is also linked to a variety of additional resources, which facilitates cross-referencing of a particular plasmid to protein annotations and experimental data. Plasmid samples can be requested directly through the website. We have also developed a novel strategy to avoid the most common concern encountered when distributing plasmids namely, the complexity of material transfer agreement (MTA) processing and the resulting delays this causes. The Expedited Process MTA, in which we created a network of institutions that agree to the terms of transfer in advance of a material request, eliminates these delays. Our hope is that by creating a repository of expression-ready plasmids and expediting the process for receiving these plasmids, we will help accelerate the accessibility and pace of scientific discovery.
AB - The Protein Structure Initiative Material Repository (PSI-MR; http://psimr.asu.edu) provides centralized storage and distribution for the protein expression plasmids created by PSI researchers. These plasmids are a resource that allows the research community to dissect the biological function of proteins whose structures have been identified by the PSI. The plasmid annotation, which includes the full length sequence, vector information and associated publications, is stored in a freely available, searchable database called DNASU (http://dnasu.asu.edu). Each PSI plasmid is also linked to a variety of additional resources, which facilitates cross-referencing of a particular plasmid to protein annotations and experimental data. Plasmid samples can be requested directly through the website. We have also developed a novel strategy to avoid the most common concern encountered when distributing plasmids namely, the complexity of material transfer agreement (MTA) processing and the resulting delays this causes. The Expedited Process MTA, in which we created a network of institutions that agree to the terms of transfer in advance of a material request, eliminates these delays. Our hope is that by creating a repository of expression-ready plasmids and expediting the process for receiving these plasmids, we will help accelerate the accessibility and pace of scientific discovery.
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U2 - 10.1093/nar/gkp999
DO - 10.1093/nar/gkp999
M3 - Article
C2 - 19906724
AN - SCOPUS:75549085654
SN - 0305-1048
VL - 38
SP - D743-D749
JO - Nucleic acids research
JF - Nucleic acids research
IS - SUPPL.1
M1 - gkp999
ER -