@inproceedings{3abe60fbb487401697c242f3f7065c1f,
title = "Protein identification and quantification for single cell analysis by coupling a microfluidic platform with MALDI-TOF",
abstract = "In this paper, we present our progress towards protein identification and quantification with single cell sensitivity using the hyphenation of a microfluidic platform and MALDI mass spectrometry. In our previous approach, we estimated a sensitivity in the range of high abundant proteins in single cells (∼106 protein molecules) [1]. Here, we extend these preliminary studies to achieve a true quantitative approach via identification and isotope tagging of the apoptosis marker Bcl-2.",
keywords = "ITRAQ tags, MALDI-TOF, Microfluidic, Single cell analysis",
author = "M. Yang and Chao, {T. C.} and R. Nelson and Alexandra Ros",
year = "2013",
language = "English (US)",
isbn = "9781632666246",
series = "17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013",
publisher = "Chemical and Biological Microsystems Society",
pages = "1039--1041",
booktitle = "17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013",
note = "17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013 ; Conference date: 27-10-2013 Through 31-10-2013",
}