Protein crystallization at the air/water interface induced by shearing bulk flow

Ali N. Azadani; Juan Lopez; Amir H. Hirsa

doi:10.1021/la063223x

Protein crystallization at the air/water interface induced by shearing bulk flow

Ali N. Azadani, Juan Lopez, Amir H. Hirsa

Mathematical and Statistical Sciences, School of (SoMSS)

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Abstract

We have observed 2D protein crystallization under conditions where in the absence of flow, crystallization fails to occur. Even under conditions where crystallization does occur in quiescent systems, we have found that flow can accelerate the crystallization process. By interrogating the flow responsible for this enhanced crystallization, we have correlated the enhancement with large shear in the plane of the interface. Some possible mechanisms for why interfacial shear can enhance the crystallization process are proposed.

Original language	English (US)
Pages (from-to)	5227-5230
Number of pages	4
Journal	Langmuir
Volume	23
Issue number	10
DOIs	https://doi.org/10.1021/la063223x
State	Published - May 8 2007

ASJC Scopus subject areas

General Materials Science
Condensed Matter Physics
Surfaces and Interfaces
Spectroscopy
Electrochemistry

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10.1021/la063223x

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abstract = "We have observed 2D protein crystallization under conditions where in the absence of flow, crystallization fails to occur. Even under conditions where crystallization does occur in quiescent systems, we have found that flow can accelerate the crystallization process. By interrogating the flow responsible for this enhanced crystallization, we have correlated the enhancement with large shear in the plane of the interface. Some possible mechanisms for why interfacial shear can enhance the crystallization process are proposed.",

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AB - We have observed 2D protein crystallization under conditions where in the absence of flow, crystallization fails to occur. Even under conditions where crystallization does occur in quiescent systems, we have found that flow can accelerate the crystallization process. By interrogating the flow responsible for this enhanced crystallization, we have correlated the enhancement with large shear in the plane of the interface. Some possible mechanisms for why interfacial shear can enhance the crystallization process are proposed.

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Protein crystallization at the air/water interface induced by shearing bulk flow

Abstract

ASJC Scopus subject areas

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