Programming DNA tube circumferences

Peng Yin; Rizal F. Hariadi; Sudheer Sahu; Harry M.T. Choi; Ha Park Sung; Thomas H. LaBean; John H. Reif

doi:10.1126/science.1157312

Programming DNA tube circumferences

Peng Yin, Rizal F. Hariadi, Sudheer Sahu, Harry M.T. Choi, Ha Park Sung, Thomas H. LaBean, John H. Reif

Research output: Contribution to journal › Article › peer-review

366 Scopus citations

Abstract

Synthesizing molecular tubes with monodisperse, programmable circumferences is an important goal shared by nanotechnology, materials science, and supermolecular chemistry. We program molecular tube circumferences by specifying the complementarity relationships between modular domains in a 42-base single-stranded DNA motif. Single-step annealing results in the self-assembly of long tubes displaying monodisperse circumferences of 4, 5, 6, 7, 8, 10, or 20 DNA helices.

Original language	English (US)
Pages (from-to)	824-826
Number of pages	3
Journal	Science
Volume	321
Issue number	5890
DOIs	https://doi.org/10.1126/science.1157312
State	Published - Aug 8 2008
Externally published	Yes

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title = "Programming DNA tube circumferences",

abstract = "Synthesizing molecular tubes with monodisperse, programmable circumferences is an important goal shared by nanotechnology, materials science, and supermolecular chemistry. We program molecular tube circumferences by specifying the complementarity relationships between modular domains in a 42-base single-stranded DNA motif. Single-step annealing results in the self-assembly of long tubes displaying monodisperse circumferences of 4, 5, 6, 7, 8, 10, or 20 DNA helices.",

author = "Peng Yin and Hariadi, {Rizal F.} and Sudheer Sahu and Choi, {Harry M.T.} and Sung, {Ha Park} and LaBean, {Thomas H.} and Reif, {John H.}",

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AU - Yin, Peng

AU - Hariadi, Rizal F.

AU - Sahu, Sudheer

AU - Choi, Harry M.T.

AU - Sung, Ha Park

AU - LaBean, Thomas H.

AU - Reif, John H.

PY - 2008/8/8

Y1 - 2008/8/8

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AB - Synthesizing molecular tubes with monodisperse, programmable circumferences is an important goal shared by nanotechnology, materials science, and supermolecular chemistry. We program molecular tube circumferences by specifying the complementarity relationships between modular domains in a 42-base single-stranded DNA motif. Single-step annealing results in the self-assembly of long tubes displaying monodisperse circumferences of 4, 5, 6, 7, 8, 10, or 20 DNA helices.

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JO - Science

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Programming DNA tube circumferences

Abstract

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