Programming DNA tube circumferences

Peng Yin, Rizal Hariadi, Sudheer Sahu, Harry M T Choi, Ha Park Sung, Thomas H. LaBean, John H. Reif

Research output: Contribution to journalArticle

281 Scopus citations


Synthesizing molecular tubes with monodisperse, programmable circumferences is an important goal shared by nanotechnology, materials science, and supermolecular chemistry. We program molecular tube circumferences by specifying the complementarity relationships between modular domains in a 42-base single-stranded DNA motif. Single-step annealing results in the self-assembly of long tubes displaying monodisperse circumferences of 4, 5, 6, 7, 8, 10, or 20 DNA helices.

Original languageEnglish (US)
Pages (from-to)824-826
Number of pages3
Issue number5890
StatePublished - Aug 8 2008
Externally publishedYes


ASJC Scopus subject areas

  • General

Cite this

Yin, P., Hariadi, R., Sahu, S., Choi, H. M. T., Sung, H. P., LaBean, T. H., & Reif, J. H. (2008). Programming DNA tube circumferences. Science, 321(5890), 824-826.