Principles and emerging applications of nanomagnetic materials in medicine

Veronica Clavijo-Jordan, Vikram Kodibagkar, Scott C. Beeman, Bradley D. Hann, Kevin M. Bennett

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

The development of nanometer-scale magnetic materials for biomedical applications spans the interface between the physical sciences and biology. Applications of these materials are rapidly becoming important in medicine and enable targeted therapies and diagnostics. At the same time, specific applications add focus to the development of novel magnetic materials and facilitate a deeper understanding of the physical mechanisms behind their function. This review presents a broad, nontechnical overview of the basis of magnetism in materials at the nanometer scale and describes how these materials are created, characterized, and used. Specific emerging applications in medical diagnostics and therapies are discussed, including cancer cell targeting for thermal ablation, tissue engineering, and three-dimensional noninvasive molecular imaging. Challenges in these fields are discussed, including the toxicity and delivery of magnetic nanomaterials and the sensitivity of imaging and therapeutic techniques. The development of novel nanomagnetic nanomaterials should continue to accelerate as new applications are identified and researchers uncover new mechanisms to increase and modulate magnetism at the nanometer scale.

Original languageEnglish (US)
Pages (from-to)345-365
Number of pages21
JournalWiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology
Volume4
Issue number4
DOIs
StatePublished - Jul 2012

Fingerprint

Nanomagnetics
Medicine
Nanostructures
Magnetic materials
Natural Science Disciplines
Magnetism
Molecular Imaging
Nanostructured materials
Tissue Engineering
Therapeutics
Molecular imaging
Hot Temperature
Research Personnel
Ablation
Tissue engineering
Toxicity
Cells
Neoplasms
Imaging techniques

ASJC Scopus subject areas

  • Bioengineering
  • Biomedical Engineering
  • Medicine (miscellaneous)

Cite this

Principles and emerging applications of nanomagnetic materials in medicine. / Clavijo-Jordan, Veronica; Kodibagkar, Vikram; Beeman, Scott C.; Hann, Bradley D.; Bennett, Kevin M.

In: Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology, Vol. 4, No. 4, 07.2012, p. 345-365.

Research output: Contribution to journalArticle

Clavijo-Jordan, Veronica ; Kodibagkar, Vikram ; Beeman, Scott C. ; Hann, Bradley D. ; Bennett, Kevin M. / Principles and emerging applications of nanomagnetic materials in medicine. In: Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology. 2012 ; Vol. 4, No. 4. pp. 345-365.
@article{ccd401ce95374776bb6b4a094db074d6,
title = "Principles and emerging applications of nanomagnetic materials in medicine",
abstract = "The development of nanometer-scale magnetic materials for biomedical applications spans the interface between the physical sciences and biology. Applications of these materials are rapidly becoming important in medicine and enable targeted therapies and diagnostics. At the same time, specific applications add focus to the development of novel magnetic materials and facilitate a deeper understanding of the physical mechanisms behind their function. This review presents a broad, nontechnical overview of the basis of magnetism in materials at the nanometer scale and describes how these materials are created, characterized, and used. Specific emerging applications in medical diagnostics and therapies are discussed, including cancer cell targeting for thermal ablation, tissue engineering, and three-dimensional noninvasive molecular imaging. Challenges in these fields are discussed, including the toxicity and delivery of magnetic nanomaterials and the sensitivity of imaging and therapeutic techniques. The development of novel nanomagnetic nanomaterials should continue to accelerate as new applications are identified and researchers uncover new mechanisms to increase and modulate magnetism at the nanometer scale.",
author = "Veronica Clavijo-Jordan and Vikram Kodibagkar and Beeman, {Scott C.} and Hann, {Bradley D.} and Bennett, {Kevin M.}",
year = "2012",
month = "7",
doi = "10.1002/wnan.1169",
language = "English (US)",
volume = "4",
pages = "345--365",
journal = "Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology",
issn = "1939-0041",
publisher = "John Wiley and Sons Inc.",
number = "4",

}

TY - JOUR

T1 - Principles and emerging applications of nanomagnetic materials in medicine

AU - Clavijo-Jordan, Veronica

AU - Kodibagkar, Vikram

AU - Beeman, Scott C.

AU - Hann, Bradley D.

AU - Bennett, Kevin M.

PY - 2012/7

Y1 - 2012/7

N2 - The development of nanometer-scale magnetic materials for biomedical applications spans the interface between the physical sciences and biology. Applications of these materials are rapidly becoming important in medicine and enable targeted therapies and diagnostics. At the same time, specific applications add focus to the development of novel magnetic materials and facilitate a deeper understanding of the physical mechanisms behind their function. This review presents a broad, nontechnical overview of the basis of magnetism in materials at the nanometer scale and describes how these materials are created, characterized, and used. Specific emerging applications in medical diagnostics and therapies are discussed, including cancer cell targeting for thermal ablation, tissue engineering, and three-dimensional noninvasive molecular imaging. Challenges in these fields are discussed, including the toxicity and delivery of magnetic nanomaterials and the sensitivity of imaging and therapeutic techniques. The development of novel nanomagnetic nanomaterials should continue to accelerate as new applications are identified and researchers uncover new mechanisms to increase and modulate magnetism at the nanometer scale.

AB - The development of nanometer-scale magnetic materials for biomedical applications spans the interface between the physical sciences and biology. Applications of these materials are rapidly becoming important in medicine and enable targeted therapies and diagnostics. At the same time, specific applications add focus to the development of novel magnetic materials and facilitate a deeper understanding of the physical mechanisms behind their function. This review presents a broad, nontechnical overview of the basis of magnetism in materials at the nanometer scale and describes how these materials are created, characterized, and used. Specific emerging applications in medical diagnostics and therapies are discussed, including cancer cell targeting for thermal ablation, tissue engineering, and three-dimensional noninvasive molecular imaging. Challenges in these fields are discussed, including the toxicity and delivery of magnetic nanomaterials and the sensitivity of imaging and therapeutic techniques. The development of novel nanomagnetic nanomaterials should continue to accelerate as new applications are identified and researchers uncover new mechanisms to increase and modulate magnetism at the nanometer scale.

UR - http://www.scopus.com/inward/record.url?scp=84862640598&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84862640598&partnerID=8YFLogxK

U2 - 10.1002/wnan.1169

DO - 10.1002/wnan.1169

M3 - Article

C2 - 22488879

AN - SCOPUS:84862640598

VL - 4

SP - 345

EP - 365

JO - Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology

JF - Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology

SN - 1939-0041

IS - 4

ER -