Pregnane glycosides from an antitumour fraction of Periploca sepium

Hideji itokawa; Junping Xu; Koichi Takeya

doi:10.1016/0031-9422(88)80297-8

Pregnane glycosides from an antitumour fraction of Periploca sepium

Hideji itokawa, Junping Xu, Koichi Takeya

Arizona State University

Research output: Contribution to journal › Article › peer-review

39 Scopus citations

Abstract

Three new pregnane glycosides (S-4a, S-5 and S-10) and two known pregnane glycosides (S-4b and S-6) were isolated from an antitumour fraction of the root barks of Periploca sepium. Their structures were determined by ¹H and ¹³C NMR, FABMS and SIMS spectroscopy and some chemical transformations. One of the glycosides (S-4a) contained the new aglycone Δ⁵-pregnene-3β,16β,20(R)-triol.

Original language	English (US)
Pages (from-to)	1173-1179
Number of pages	7
Journal	Phytochemistry
Volume	27
Issue number	4
DOIs	https://doi.org/10.1016/0031-9422(88)80297-8
State	Published - 1988

Keywords

Aselepiadaccae
Periploca sepium
pregnane glycoside
Δ-pregnene-3β,16α,20(S)-triol.
Δ-pregnene-3β,16β,20(R)-triol

ASJC Scopus subject areas

Biochemistry
Molecular Biology
Plant Science
Horticulture

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10.1016/0031-9422(88)80297-8

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title = "Pregnane glycosides from an antitumour fraction of Periploca sepium",

abstract = "Three new pregnane glycosides (S-4a, S-5 and S-10) and two known pregnane glycosides (S-4b and S-6) were isolated from an antitumour fraction of the root barks of Periploca sepium. Their structures were determined by 1H and 13C NMR, FABMS and SIMS spectroscopy and some chemical transformations. One of the glycosides (S-4a) contained the new aglycone Δ5-pregnene-3β,16β,20(R)-triol.",

keywords = "Aselepiadaccae, Periploca sepium, pregnane glycoside, Δ-pregnene-3β,16α,20(S)-triol., Δ-pregnene-3β,16β,20(R)-triol",

author = "Hideji itokawa and Junping Xu and Koichi Takeya",

year = "1988",

doi = "10.1016/0031-9422(88)80297-8",

language = "English (US)",

volume = "27",

pages = "1173--1179",

journal = "Phytochemistry",

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T1 - Pregnane glycosides from an antitumour fraction of Periploca sepium

AU - itokawa, Hideji

AU - Xu, Junping

AU - Takeya, Koichi

PY - 1988

Y1 - 1988

N2 - Three new pregnane glycosides (S-4a, S-5 and S-10) and two known pregnane glycosides (S-4b and S-6) were isolated from an antitumour fraction of the root barks of Periploca sepium. Their structures were determined by 1H and 13C NMR, FABMS and SIMS spectroscopy and some chemical transformations. One of the glycosides (S-4a) contained the new aglycone Δ5-pregnene-3β,16β,20(R)-triol.

AB - Three new pregnane glycosides (S-4a, S-5 and S-10) and two known pregnane glycosides (S-4b and S-6) were isolated from an antitumour fraction of the root barks of Periploca sepium. Their structures were determined by 1H and 13C NMR, FABMS and SIMS spectroscopy and some chemical transformations. One of the glycosides (S-4a) contained the new aglycone Δ5-pregnene-3β,16β,20(R)-triol.

KW - Aselepiadaccae

KW - Periploca sepium

KW - pregnane glycoside

KW - Δ-pregnene-3β,16α,20(S)-triol.

KW - Δ-pregnene-3β,16β,20(R)-triol

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DO - 10.1016/0031-9422(88)80297-8

M3 - Article

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SN - 0031-9422

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EP - 1179

JO - Phytochemistry

JF - Phytochemistry

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ER -

Pregnane glycosides from an antitumour fraction of Periploca sepium

Abstract

Keywords

ASJC Scopus subject areas

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