Pregnane glycosides from an antitumour fraction of Periploca sepium

Hideji itokawa, Jun-Ping Xu, Koichi Takeya

Research output: Contribution to journalArticle

36 Citations (Scopus)

Abstract

Three new pregnane glycosides (S-4a, S-5 and S-10) and two known pregnane glycosides (S-4b and S-6) were isolated from an antitumour fraction of the root barks of Periploca sepium. Their structures were determined by 1H and 13C NMR, FABMS and SIMS spectroscopy and some chemical transformations. One of the glycosides (S-4a) contained the new aglycone Δ5-pregnene-3β,16β,20(R)-triol.

Original languageEnglish (US)
Pages (from-to)1173-1179
Number of pages7
JournalPhytochemistry
Volume27
Issue number4
DOIs
StatePublished - Jan 1 1988
Externally publishedYes

Fingerprint

Periploca
Sepia
glycosides
Pregnenes
S 10
S 6
Glycosides
Secondary ion mass spectrometry
Spectrum Analysis
Nuclear magnetic resonance
Spectroscopy
spectroscopy
bark
pregnane glycoside

Keywords

  • Aselepiadaccae
  • Periploca sepium
  • pregnane glycoside
  • Δ-pregnene-3β,16α,20(S)-triol.
  • Δ-pregnene-3β,16β,20(R)-triol

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Plant Science
  • Horticulture

Cite this

Pregnane glycosides from an antitumour fraction of Periploca sepium. / itokawa, Hideji; Xu, Jun-Ping; Takeya, Koichi.

In: Phytochemistry, Vol. 27, No. 4, 01.01.1988, p. 1173-1179.

Research output: Contribution to journalArticle

itokawa, Hideji ; Xu, Jun-Ping ; Takeya, Koichi. / Pregnane glycosides from an antitumour fraction of Periploca sepium. In: Phytochemistry. 1988 ; Vol. 27, No. 4. pp. 1173-1179.
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