TY - JOUR
T1 - Posterior cricoarytenoid muscle dynamics in canines and humans
AU - Chhetri, Dinesh K.
AU - Neubauer, Juergen
AU - Sofer, Elazar
N1 - Publisher Copyright:
© 2014 The American Laryngological, Rhinological and Otological Society, Inc.
PY - 2014/10/1
Y1 - 2014/10/1
N2 - Objectives/Hypothesis: The posterior cricoarytenoid (PCA) muscle is the sole abductor of the glottis and serves important functions during respiration, phonation, cough, and sniff. The present study examines vocal fold abduction dynamics during PCA muscle activation. Study Design: Basic science study using an in vivo canine model and human subjects. Methods: In four canines and five healthy humans vocal fold abduction time was measured using high-speed video recording. In the canines, PCA muscle activation was achieved using graded stimulation of the PCA nerve branch. The human subjects performed coughing and sniffing tasks. High-speed video and audio signals were concurrently recorded. Results: In the canines, the vocal fold moved posteriorly, laterally, and superiorly during abduction. Average time to reach 10%, 50%, and 90% abduction was 23, 50, and 100 ms with low stimulation; 24, 58, and 129 ms with medium stimulation; and 21, 49, and 117 ms with high-level stimulation, respectively. In the humans, 100% abduction times for coughing and sniffing tasks were 79 and 193 ms, respectively. Conclusions: The PCA abduction times in canines are within the range in humans. The results also further support the notion that PCA muscles are fully active during cough.
AB - Objectives/Hypothesis: The posterior cricoarytenoid (PCA) muscle is the sole abductor of the glottis and serves important functions during respiration, phonation, cough, and sniff. The present study examines vocal fold abduction dynamics during PCA muscle activation. Study Design: Basic science study using an in vivo canine model and human subjects. Methods: In four canines and five healthy humans vocal fold abduction time was measured using high-speed video recording. In the canines, PCA muscle activation was achieved using graded stimulation of the PCA nerve branch. The human subjects performed coughing and sniffing tasks. High-speed video and audio signals were concurrently recorded. Results: In the canines, the vocal fold moved posteriorly, laterally, and superiorly during abduction. Average time to reach 10%, 50%, and 90% abduction was 23, 50, and 100 ms with low stimulation; 24, 58, and 129 ms with medium stimulation; and 21, 49, and 117 ms with high-level stimulation, respectively. In the humans, 100% abduction times for coughing and sniffing tasks were 79 and 193 ms, respectively. Conclusions: The PCA abduction times in canines are within the range in humans. The results also further support the notion that PCA muscles are fully active during cough.
KW - Cough
KW - High-speed videoendoscopy
KW - Posterior cricoarytenoid muscle
KW - Sniff
KW - Vocal fold abduction
KW - Voice production
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U2 - 10.1002/lary.24742
DO - 10.1002/lary.24742
M3 - Article
C2 - 24781959
AN - SCOPUS:84907899527
SN - 0023-852X
VL - 124
SP - 2363
EP - 2367
JO - Laryngoscope
JF - Laryngoscope
IS - 10
ER -