Positive allosteric modulators of type 5 metabotropic glutamate receptors (mGluR5) and their therapeutic potential for the treatment of CNS disorders

Physics & Astronomy

• central nervous system 93%
• drugs 66%
• modulators 56%
• disorders 50%
• learning 35%
• schizophrenia 28%
• extinction 28%
• anxiety 27%
• Parkinson disease 26%
• pain 23%
• deletion 23%
• genes 19%
• animals 16%
• plastic properties 15%
• activation 13%
• characterization 9%
• molecules 8%
• performance 7%

Medicine & Life Sciences

• Metabotropic Glutamate 5 Receptor 100%
• Central Nervous System Diseases 72%
• Psychological Extinction 38%
• Drug-Seeking Behavior 24%
• Learning 24%
• Fragile X Syndrome 21%
• Gene Deletion 18%
• Gastroesophageal Reflux 17%
• Neuronal Plasticity 15%
• Antipsychotic Agents 15%
• Chronic Pain 15%
• Substance-Related Disorders 14%
• Parkinson Disease 13%
• Pharmaceutical Preparations 13%
• Schizophrenia 13%
• Memory 12%
• Anxiety 11%
• Aptitude 11%
• Pharmacology 11%
• Depression 10%
• Therapeutics 10%
• Animals 8%

Chemical Compounds

• Disorder 56%
• Antipsychotic Agent 35%
• Drug 35%
• Plastic Property 25%
• Antagonist 20%
• Molecule 7%