Positional assignment of differentially substituted bisaminoacylated pdCpAs

David J. Maloney, Noha Ghanem, Jia Zhou, Sidney Hecht

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

The synthesis and NMR analysis of a 2′-O-alanyl, 3′-O-[1- 13C]valyl-pdCpA derivative has permitted the definitive assignment of the positions of acylation of tandemly activated pdCpAs, and the bisaminoacylated transfer RNAs derived therefrom.

Original languageEnglish (US)
Pages (from-to)3135-3138
Number of pages4
JournalOrganic and Biomolecular Chemistry
Volume5
Issue number19
DOIs
StatePublished - 2007
Externally publishedYes

Fingerprint

ribonucleic acids
acylation
Acylation
nuclear magnetic resonance
synthesis
Transfer RNA
Nuclear magnetic resonance
Derivatives
5'-phospho-2'-deoxyribocytidylylriboadenosine

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Chemistry(all)

Cite this

Positional assignment of differentially substituted bisaminoacylated pdCpAs. / Maloney, David J.; Ghanem, Noha; Zhou, Jia; Hecht, Sidney.

In: Organic and Biomolecular Chemistry, Vol. 5, No. 19, 2007, p. 3135-3138.

Research output: Contribution to journalArticle

Maloney, David J. ; Ghanem, Noha ; Zhou, Jia ; Hecht, Sidney. / Positional assignment of differentially substituted bisaminoacylated pdCpAs. In: Organic and Biomolecular Chemistry. 2007 ; Vol. 5, No. 19. pp. 3135-3138.
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