Abstract
Electrochemical impedance spectroscopy (EIS) measures the frequency spectrum of an electrochemical interface to resist an alternating current. This method allows label-free and noninvasive studies on interfacial adsorption and molecular interactions and has applications in biosensing and drug screening. Although powerful, traditional EIS lacks spatial resolution or imaging capability, hindering the study of heterogeneous electrochemical processes on electrodes. We have recently developed a plasmonics-based electrochemical impedance technique to image local electrochemical impedance with a submicron spatial resolution and a submillisecond temporal resolution. In this review, we provide a systematic description of the theory, instrumentation, and data analysis of this technique. To illustrate its present and future applications, we further describe several selected samples analyzed with this method, including protein microarrays, two-dimensional materials, and single cells. We conclude by summarizing the technique's unique features and discussing the remaining challenges and new directions of its application.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 183-200 |
| Number of pages | 18 |
| Journal | Annual Review of Analytical Chemistry |
| Volume | 10 |
| DOIs | |
| State | Published - Jun 12 2017 |
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Keywords
- Electrochemical impedance microscopy
- Electrochemical impedance spectroscopy
- Plasmonic imaging
- Single-cell imaging
- Surface plasmon resonance
ASJC Scopus subject areas
- Analytical Chemistry
Cite this
Plasmonic imaging of electrochemical impedance. / Yuan, Liang; Tao, Nongjian; Wang, Wei.
In: Annual Review of Analytical Chemistry, Vol. 10, 12.06.2017, p. 183-200.Research output: Contribution to journal › Review article
}
TY - JOUR
T1 - Plasmonic imaging of electrochemical impedance
AU - Yuan, Liang
AU - Tao, Nongjian
AU - Wang, Wei
PY - 2017/6/12
Y1 - 2017/6/12
N2 - Electrochemical impedance spectroscopy (EIS) measures the frequency spectrum of an electrochemical interface to resist an alternating current. This method allows label-free and noninvasive studies on interfacial adsorption and molecular interactions and has applications in biosensing and drug screening. Although powerful, traditional EIS lacks spatial resolution or imaging capability, hindering the study of heterogeneous electrochemical processes on electrodes. We have recently developed a plasmonics-based electrochemical impedance technique to image local electrochemical impedance with a submicron spatial resolution and a submillisecond temporal resolution. In this review, we provide a systematic description of the theory, instrumentation, and data analysis of this technique. To illustrate its present and future applications, we further describe several selected samples analyzed with this method, including protein microarrays, two-dimensional materials, and single cells. We conclude by summarizing the technique's unique features and discussing the remaining challenges and new directions of its application.
AB - Electrochemical impedance spectroscopy (EIS) measures the frequency spectrum of an electrochemical interface to resist an alternating current. This method allows label-free and noninvasive studies on interfacial adsorption and molecular interactions and has applications in biosensing and drug screening. Although powerful, traditional EIS lacks spatial resolution or imaging capability, hindering the study of heterogeneous electrochemical processes on electrodes. We have recently developed a plasmonics-based electrochemical impedance technique to image local electrochemical impedance with a submicron spatial resolution and a submillisecond temporal resolution. In this review, we provide a systematic description of the theory, instrumentation, and data analysis of this technique. To illustrate its present and future applications, we further describe several selected samples analyzed with this method, including protein microarrays, two-dimensional materials, and single cells. We conclude by summarizing the technique's unique features and discussing the remaining challenges and new directions of its application.
KW - Electrochemical impedance microscopy
KW - Electrochemical impedance spectroscopy
KW - Plasmonic imaging
KW - Single-cell imaging
KW - Surface plasmon resonance
UR - http://www.scopus.com/inward/record.url?scp=85020704876&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85020704876&partnerID=8YFLogxK
U2 - 10.1146/annurev-anchem-061516-045150
DO - 10.1146/annurev-anchem-061516-045150
M3 - Review article
C2 - 28301751
AN - SCOPUS:85020704876
VL - 10
SP - 183
EP - 200
JO - Annual Review of Analytical Chemistry
JF - Annual Review of Analytical Chemistry
SN - 1936-1327
ER -