Plasma pyridoxal 5'-phosphate concentration and dietary vitamin B-6 intake in free-living, low-income elderly people

M. M. Manore, L. A. Vaughan, S. S. Carroll, J. E. Leklem

    Research output: Contribution to journalArticle

    35 Scopus citations

    Abstract

    Free-living, elderly persons (aged ≥ 60 y, n = 198) were recruited to determine the effects of age, sex, health status, dietary vitamin B-6 intakes, and B-6 supplement use on plasma pyridoxal 5'-phosphate (PLP). Vitamin B-6 intakes were determined from 3-d diet records; supplementation was based on self-reported brand and frequency data. Fasting blood samples were analyzed for PLP. Subjects were primarily low-income Caucasians. There was no linear relationship between dietary vitamin B-6 intake, age, sex or health status, and PLP while accounting for supplemental vitamin B-6 use. PLP, however, was negatively correlated with age (p < 0.001) in individuals with PLP values between 32 and 90 nmol/L. Vitamin B-6 status was low (PLP < 32 nmol/L) in 32% of this elderly population (n = 198) and could be attributed to low dietary vitamin B-6 intakes and/or the presence of health problems reported to alter vitamin B-6 status. This research suggests that low vitamin B-6 status is prevalent in low-income, elderly persons, especially those with multiple health problems.

    Original languageEnglish (US)
    Pages (from-to)339-345
    Number of pages7
    JournalAmerican Journal of Clinical Nutrition
    Volume50
    Issue number2
    DOIs
    StatePublished - Jan 1 1989

    ASJC Scopus subject areas

    • Medicine (miscellaneous)
    • Nutrition and Dietetics

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